14091-94-2

Basic information

• Product Name: 1-Phenyl-3-morpholino-2-butene-1-one
• Synonyms: 1-Phenyl-3-morpholino-2-butene-1-one;3-Morpholino-1-phenyl-2-buten-1-one;3-Morpholinocrotonophenone
• CAS NO: 14091-94-2
• Molecular Formula: C₁₄H₁₇NO₂
• Molecular Weight: 231.29
• Mol File: 14091-94-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Phenyl-3-morpholino-2-butene-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-3-morpholino-2-butene-1-one(14091-94-2)
• EPA Substance Registry System: 1-Phenyl-3-morpholino-2-butene-1-one(14091-94-2)

Safety Data

• Hazardous Substances Data: 14091-94-2(Hazardous Substances Data)

Usage

Appearance

Yellow solid

Molecular weight

231.29 g/mol

Uses

Versatile intermediate used in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and dyes. Commonly used as a building block in the production of antihistamine drugs and in the development of new chemical entities for potential therapeutic applications.

Synthesis

Synthesized through the reaction of 1-phenyl-2-butanone and morpholine

Structural features

Unique structural features make it a valuable component in the creation of diverse chemical structures.

Upstream product

• 70-11-1 α-bromoacetophenone 
• 5309-93-3 N-thioacetylmorpholine 
• 145930-93-4 4-[1-(2-Oxo-2-phenyl-ethylsulfanyl)-ethylidene]-morpholin-4-ium; bromide 
• 110-91-8 morpholine 
• 74896-63-2 1-phenyl-3-ethylsulfinyl-2-buten-1-one 
• 70769-72-1 1-phenyl-3-ethylsulfenyl-2-buten-1-one 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 53067-92-8 2-(2-acetylphenyl)-1-phenylethan-1-one 
• 1190830-89-7 5-hydroxy-1,6-diphenyl-3-(4-morpholinyl)hex-2-en-1,6-dione 
• 26826-99-3 6,6,6-trichloro-3-morpholin-4-yl-1-phenyl-5-phenylcarbamoyloxy-hex-2-en-1-one 
• 96517-67-8 4-Methyl-2-(2-oxo-2-phenyl-ethylsulfanyl)-6-phenyl-nicotinonitrile 
• 96517-63-4 (3-Cyano-4-methyl-6-phenyl-pyridin-2-ylsulfanyl)-acetic acid methyl ester 
• 96517-65-6 2-(3-Cyano-4-methyl-6-phenyl-pyridin-2-ylsulfanyl)-acetamide 
• 96517-66-7 2-Cyanomethylsulfanyl-4-methyl-6-phenyl-nicotinonitrile 
• 96517-76-9 3-Amino-4-methyl-6-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid methyl ester 
• 96517-64-5 ethyl (3-cyano-6-phenyl-4-methylpyridinylthio)acetate 
• 96517-77-0 6-phenyl-3-amino-4-methylthieno[2,3-b]-pyridine-2-carboxamide 
• 52505-67-6 (3-amino-4-methyl-6-phenyl-thieno[2,3-b]pyridin-2-yl)-phenyl-methanone 
• 52505-64-3 3-Amino-4-methyl-6-phenyl-thieno<2,3-b>pyridin-2-carbonsaeureethylester 

Relevant articles and documents

Reaction of arynes with vinylogous amides: Nucleophilic addition to the ortho-quinodimethide intermediate

The reaction of arynes with vinylogous amides containing no free N-H bonds proceeds in a [2 + 2] cycloaddition fashion at ambient temperature. The electronic properties of the vinylogous amides allow for the cycloadducts undergoing a facile ring-opening p

The Substitution Reaction of 2-Alkylthio-1-alkenyl and 2-Alkylsulfinyl-1-alkenyl Ketones with Amines: Preparation of 2-Amino-1-alkenyl Ketones

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