140925-55-9Relevant academic research and scientific papers
Formal total synthesis of spirangien A
Gregg, Claire,Gunawan, Christian,Ng, Audrey Wai Yi,Wimala, Samantha,Wickremasinghe, Sonali,Rizzacasa, Mark A.
, p. 516 - 519 (2013/04/10)
A formal total synthesis of the spiroketal containing cytotoxic myxobacteria metabolite spirangien A (1) is described. The approach utilizes a late introduction of the C20 alcohol that mirrors the biosynthesis of this compound. The key steps involved a hi
Studies in Polypropionate Synthesis: A General Approach to the Synthesis of Stereopentads.
Paterson, Ian,Channon, Julia A.
, p. 797 - 800 (2007/10/02)
A general protocol for the synthesis of specific isomers of the stereopentad 1 from the α-chiral ethyl ketones (R)- and (S)-2 has been developed.From (S)-2, this involves stepwise elaboration of each of the three aldol adducts 3, 4 and 5 by stereoselectiv
