140927-12-4Relevant articles and documents
Synthesis of epibatidine isomers: endo-5- and 6- (6′-chloro-3′-pyridyl-2-azabicyclo[2.2.1]heptanes
Cox,Malpass,Gordon,Rosen
, p. 2372 - 2379 (2007/10/03)
Synthesis of the title compounds is described; detailed NMR data are provided in support of the proposed stereostructures. The 5- and 6-endo-compounds show high selectivity for α4β2 versus α7 nAChR subtypes; in contrast, the exo-stereoisomers show compara
Synthesis and Muscarinic Receptor Activity of Ester Derivatives of 2-Substituted 2-Azabicycloheptan-5-ol and -6-ol
Carroll, F. Ivy,Abraham, Phillip,Chemburkar, Sanjay,He, Xu-Chang,Mascarella, S. Wayne,et al.
, p. 2184 - 2191 (2007/10/02)
Radioligand binding affinities of four new muscarinic antagonists and six potential muscarinic agonists which possess the 2-alkyl-2-azabicycloheptane ring system have been determined in rat heart, rat brain, and m1- or m3-tran