Synthesis of constrained bicyclic dipeptide mimetics

DOI: 10.1016/S0040-4039(97)10422-1

Source and publish data:

Tetrahedron Letters p. 8807 - 8810 (1997)

Update date:2022-08-05

Topics:

Authors:

Siddiqui, M. Arshad

Preville, Patrice

Tarazi, Micheline

Warder, Scott E.

Eby, Paul

Gorseth, Elise

Puumala, Karen

DiMaio, John

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Article abstract of DOI:10.1016/S0040-4039(97)10422-1

An efficient synthesis of constrained bicyclic peptidomimetics of (R)-Phe-Pro dipeptide is described, Such mimetics may provide an opportunity to develop inhibitors of thrombin possessing the desired pharmacological features.

Full text of DOI:10.1016/S0040-4039(97)10422-1

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