141277-75-0Relevant academic research and scientific papers
Scandium trisdodecylsulfate (STDS). A new type of Lewis acid that forms stable dispersion systems with organic substrates in water and accelerates aldol reactions much faster in water than in organic solvents
Kobayashi, Shu,Wakabayashi, Takeshi
, p. 5389 - 5392 (1998)
A new type of Lewis acid, scandium trisdodecylsulfate (STDS), was prepared. In the presence of a catalytic amount of STDS, aldol reactions of silyl enol ethers with aldehydes proceeded smoothly in water without using any organic solvents. It was proven th
Lewis base-promoted aldol reaction of dimethylsilyl enolates in aqueous dimethylformamide: Use of calcium chloride as a Lewis base catalyst
Miura, Katsukiyo,Nakagawa, Takahiro,Hosomi, Akira
, p. 536 - 537 (2007/10/03)
In the presence of CaCl2, dimethylsilyl (DMS) enolates smoothly reacted with aldehydes under mild conditions to give aldol adducts in good to high yields. The catalytic activities of various metal and tetrabutylammonium salts have revealed that CaCl2 works as a Lewis base catalyst to activate DMS enolates. The CaCl2-promoted reaction proceeded even in the presence of water or in pure water. This catalytic system was applicable to the aldol reaction with aqueous aldehydes such as formalin. Copyright
Highly diastereoselective aldol synthesis from α-iodo ketones in aqueous media
Shibata, Ikuya,Kawasaki, Masatsugu,Yasuda, Makoto,Baba, Akio
, p. 689 - 690 (2007/10/03)
Highly diastereoselective aldol synthesis from α-iodo ketones was promoted under aqueous conditions by a distannane system, (n-Bu3Sn)2, n-Bu2SnF2 and HMPA. Aqueous solutions of acetaldehyde, formaldehyde and piv
