1414948-86-9

Upstream product

• 209624-66-8 3-hydroxy-4-methoxy-5-methylbenzaldehyde 
• 575444-12-1 3-(benzyloxy)-4-methoxy-5-methylbenzaldehyde 
• 1414948-51-8 (Z)-methyl 3-[3-(benzyloxy)-4-methoxy-5-methylphenyl]-2-[(tert-butoxycarbonyl)amino]acrylate 
• 1414948-54-1 (S)-methyl 3-[3-(benzyloxy)-4-methoxy-5-methylphenyl]-2-[(tert-butoxycarbonyl)amino]propanoate 
• 100-39-0 benzyl bromide 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1414948-46-1 (S)-5-(2-amino-3,3-dimethoxypropyl)-2-methoxy-3-methylphenol 
• 1414948-88-1 C₂₈H₃₃NO₆ 
• 1414948-61-0 (1R,3S)-3-(dimethoxymethyl)-1-{(R)-2,2-dimethyl-3-[(4-nitrophenyl)sulfonyl]oxazolidin-4-yl}-7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinolin-8-ol 
• 1414948-63-2 (1R,3S)-2-chloroethyl 8-benzyloxy-3-(dimethoxymethyl)-1-{(R)-2,2-dimethyl-3-[(4-nitrophenyl)sulfonyl]oxazolidin-4-yl}-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-65-4 (1R,3S)-2-chloroethyl 1-[(R)-1-amino-2-hydroxyethyl]-8-benzyloxy-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-69-8 (1R,3S)-2-chloroethyl 8-(benzyloxy)-3-(dimethoxymethyl)-7-methoxy-6-methyl-1-[(R)-6-oxomorpholin-3-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-72-3 (1R,3S)-2-chloroethyl 8-(benzyloxy)-3-(dimethoxymethyl)-7-methoxy-6-methyl-1-[(R)-6-oxo-3,6-dihydro-2H-1,4-oxazin-3-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-74-5 (1R,3S)-2-chloroethyl 8-(benzyloxy)-1-{(3R,5R)-5-[6-(benzyloxy)-7-hydroxybenzo[d][1,3]dioxol-4-yl]-6-oxomorpholin-3-yl}-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-76-7 (1R,3S)-2-chloroethyl 8-(benzyloxy)-1-{(4R,6R)-4-[6-(benzyloxy)-7-{[(trifluoromethyl)sulfonyl]oxy}benzo[d][1,3]dioxol-4-yl]-9,9,10,10-tetramethyl-3-oxo-2,8-dioxa-5-aza-9-silaundecan-6-yl}-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-78-9 (1R,3S)-2-chloroethyl 8-(benzyloxy)-1-[(R)-1-({(R)-1-[6-(benzyloxy)-7-{[(trifluoromethyl)sulfonyl]oxy}benzo[d][1,3]dioxol-4-yl]-2-hydroxyethyl}amino)-2-{(tert-butyldimethylsilyl)oxy}ethyl]-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-80-3 (3R,5R,6R,12S,12aS)-2-chloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-{[(trifluoromethyl)sulfonyl]oxy}benzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 1414948-82-5 (3R,5R,6R,12S,12aS)-2-chloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 442663-35-6 (3R,5R,6R,12S,12aS)-2,2,2-trichloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 1414948-90-5 C₃₂H₃₉N₃O₉S 

Relevant academic research and scientific papers

Synthetic studies toward ecteinascidin 743 (trabectedin)

An alternative synthetic route to an intermediate in the synthesis of ecteinascidin 743 has been established by using a Pictet-Spengler reaction and a Friedel-Crafts type reaction.