1414948-95-0

Upstream product

• 1414948-93-8 C₄₃H₄₄ClF₃N₂O₁₄S 
• 1414948-90-5 C₃₂H₃₉N₃O₉S 
• 1414948-82-5 (3R,5R,6R,12S,12aS)-2-chloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 1414948-80-3 (3R,5R,6R,12S,12aS)-2-chloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-{[(trifluoromethyl)sulfonyl]oxy}benzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 1414948-78-9 (1R,3S)-2-chloroethyl 8-(benzyloxy)-1-[(R)-1-({(R)-1-[6-(benzyloxy)-7-{[(trifluoromethyl)sulfonyl]oxy}benzo[d][1,3]dioxol-4-yl]-2-hydroxyethyl}amino)-2-{(tert-butyldimethylsilyl)oxy}ethyl]-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-72-3 (1R,3S)-2-chloroethyl 8-(benzyloxy)-3-(dimethoxymethyl)-7-methoxy-6-methyl-1-[(R)-6-oxo-3,6-dihydro-2H-1,4-oxazin-3-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-69-8 (1R,3S)-2-chloroethyl 8-(benzyloxy)-3-(dimethoxymethyl)-7-methoxy-6-methyl-1-[(R)-6-oxomorpholin-3-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-65-4 (1R,3S)-2-chloroethyl 1-[(R)-1-amino-2-hydroxyethyl]-8-benzyloxy-3-(dimethoxymethyl)-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-63-2 (1R,3S)-2-chloroethyl 8-benzyloxy-3-(dimethoxymethyl)-1-{(R)-2,2-dimethyl-3-[(4-nitrophenyl)sulfonyl]oxazolidin-4-yl}-7-methoxy-6-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1414948-61-0 (1R,3S)-3-(dimethoxymethyl)-1-{(R)-2,2-dimethyl-3-[(4-nitrophenyl)sulfonyl]oxazolidin-4-yl}-7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinolin-8-ol 
• 1414948-88-1 C₂₈H₃₃NO₆ 
• 1414948-86-9 C₂₇H₂₉NO₆ 
• 1414948-56-3 (S)-benzyl {3-[3-(benzyloxy)-4-methoxy-5-methylphenyl]-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate 
• 1414948-54-1 (S)-methyl 3-[3-(benzyloxy)-4-methoxy-5-methylphenyl]-2-[(tert-butoxycarbonyl)amino]propanoate 

Downstream Products

• 442663-35-6 (3R,5R,6R,12S,12aS)-2,2,2-trichloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 

Relevant academic research and scientific papers

Synthetic studies toward ecteinascidin 743 (trabectedin)

An alternative synthetic route to an intermediate in the synthesis of ecteinascidin 743 has been established by using a Pictet-Spengler reaction and a Friedel-Crafts type reaction.