1415675-06-7

Upstream product

• 80318-54-3 N-(4'-nitrobenzoyl)-4-hydroxybenzylamine 
• 696-60-6 4-aminomethylphenol 
• 40782-54-5 4-heptyloxybenzoyl chloride 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 1415669-52-1 2-(N-(4-((4-(heptyloxy)benzoyl)oxy)benzyl)-4-(2-(4-methoxyphenyl)acetamido)benzamido)-acetic acid 
• 1415675-07-8 4-((N-(2-(tert-butoxy)-2-oxoethyl)-4-(2-(4-methoxyphenyl)acetamido)benzamido)-methyl)phenyl 4-(heptyloxy)benzoate 
• 1415671-30-5 4-((4-amino-N-(2-(tert-butoxy)-2-oxoethyl)benzamido)methyl)phenyl 4-(heptyloxy)benzoate 
• 1415675-10-3 tert-butyl 2-(N-(4-hydroxybenzyl)-4-(2-(4-methoxyphenyl)acetamido)benzamido)acetate 

Relevant academic research and scientific papers

NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS

Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1 (7-36), GLP-1 (9-36), oxyntomodulin and exendin variants.