1415965-06-8

Upstream product

• 98-86-2 acetophenone 
• 1415964-94-1 5-(2-chloro-6-methylquinolin-3-yl)-3-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide 
• 105-36-2 ethyl bromoacetate 
• 73568-27-1 2-chloro-6-methylquinoline-3-carbaldehyde 
• 335398-84-0 C₁₉H₁₄ClNO 

Relevant academic research and scientific papers

Synthesis of new quinoline-2-pyrazoline-based thiazolinone derivatives as potential antimicrobial agents

A series of 2-(5-(2-chloro-6-methylquinolin-3-yl)-3-(aryl)-4,5-dihydro-1H- pyrazol-1-yl)thiazol-4(5H)ones (4a-l) were synthesized and characterized by IR, 1H NMR, 13C NMR, and mass spectra. All the synthesized compounds were tested for their in vitro antimicrobial activity against Escherichia coli (MTCC 443), Pseudomonas aeruginosa (MTCC 1688), Staphylococcus aureus (MTCC 96), Streptococcus pyogenes (MTCC 442), Candida albicans (MTCC 227), Aspergillus niger (MTCC 282), and Aspergillus clavatus (MTCC 1323) by serial broth dilution. Compounds 4e, 4f, 4g, 4i, 4j, and 4l were the most distinctive derivatives identified in present study because of their remarkable in vitro antimicrobial potency.