141602-25-7

Usage

Uses

Used in Pharmaceutical Industry:
Pyrimidine, 4-chloro-6-ethyl(9CI) is used as a building block in the synthesis of pharmaceuticals for its unique chemical properties and potential to contribute to the development of new drugs. Its specific structure allows for the creation of various drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Pyrimidine, 4-chloro-6-ethyl(9CI) serves as a key component in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique chemical properties enable the development of effective and targeted agrochemical products.
Used in Medicinal Chemistry Research:
Pyrimidine, 4-chloro-6-ethyl(9CI) is utilized as a research target in medicinal chemistry, where its specific structure and properties are investigated for potential applications in drug discovery and development. Its unique features make it an interesting compound for further exploration and understanding of its potential therapeutic effects and mechanisms of action.
Overall, Pyrimidine, 4-chloro-6-ethyl(9CI) holds significant potential in various industries due to its unique chemical properties and specific structure, making it a valuable compound for research, synthesis, and development of new pharmaceuticals, agrochemicals, and other chemical products.

Upstream product

• 124703-78-2 6-ethyl-4(3H)-pyrimidinone 
• 128-08-5 N-Bromosuccinimide 
• 124703-78-2 6-ethylpyrimidin-4-ol 
• 107-06-2 1,2-dichloro-ethane 
• 6554-65-0 2,4-dichloro-6-ethylpyrimidine 
• 15043-03-5 6-ethylpyrimidine-2,4(1H,3H)-dione 
• 30414-53-0 methyl propanoyl acetate 

Downstream Products

• 856160-67-3 6-ethylpyrimidin-4-amine 
• 30537-73-6 4-ethylpyrimidine 
• 182369-73-9 2-(2,4-difluorophenyl)-3-(pyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 

Relevant academic research and scientific papers

Synthesis method of voriconazole impurity B

The invention relates to a synthesis method of a voriconazole impurity B. The synthesis method of the voriconazole impurity B comprises the steps of firstly, dissolving formamidine acetate and sodiumtert-butoxide in methyl alcohol, conducting stirring und

INDOLE AND AZAINDOLE MODULATORS OF THE ALPHA 7 NACHR

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a pharmaceutically acceptable salt thereof.

Preparation of triazoles by organometallic addition to ketones and intermediates therefor

A process for the preparation of a compound of the formula: or an acid addition or base salt thereof, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and trifluoromethyl; R1 is C1-C6 alkyl; and “Het” is pyrimidinyl optionally substituted by 1 to 3 substituents each independently selected from C1-C4 alkyl, C1-C4 alkoxy, halo, oxo, benzyl and benzyloxy, comprising reacting a compound of the formula: with a compound of the formula wherein X is chloro, bromo or iodo, the reaction taking place in the presence of zinc; at least one of iodine or a Lewis acid; and an aprotic organic solvent: optionally further reacting the resulting compound with an acid or base to form the corresponding acid addition or base salt thereof.

REMEDIES OR PREVENTIVES FOR AIDS

The present invention is to provide the combined use of one kind or two or more kinds of a quinolone carboxylic acid having anti-HIV activity and one kind or two or more kinds of a reverse transcriptase inhibitor or HIV protease inhibitor, and an AIDS therapeutic agent or preventive agent containing as its active ingredients one kind or two or more kinds of a quinolone carboxylic acid having anti-HIV activity and one kind or two or more kinds of a reverse transcriptase inhibitor or HIV protease inhibitor.

Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent

Disclosed are an aryl group- or heterocyclic group-substituted aminoquinolone compound represented by the formula (Ia), (Ib) or (Ic): STR1 wherein each of the substitutents are defined in the specification, or a salt of the compound, and an AIDS curing agent containing the same as an effective ingredient.

Aminopyrimidine derivatives as microbicides, insecticides and acaricides

Compounds of formula I STR1 where R1 -R5, R8, R13, m and n are as defined herein. The novel compounds have valuable biocidal properties. They can be used in crop protection for protecting cultivated plants against attack by pests, and for controlling those pests.

Large Scale Synthesis of 4-Ethylpyrimidine

The reaction of methyl propionyl acetate with formamidine acetate in the presence of sodium methoxide produces 6-ethyl-4(3H)-pyrimidinone (1) in 67percent isolated yield.Reaction with phosphorus oxychloride and subsequent catalytic hydrogenolysis affords 4-ethylpyrimidine (3) in 41percent overall yield.