1418143-24-4

Basic information

• Product Name: 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile
• Synonyms: 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile
• CAS NO: 1418143-24-4
• Molecular Weight: 363.849
• Mol File: 1418143-24-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile(1418143-24-4)
• EPA Substance Registry System: 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile(1418143-24-4)

Safety Data

• Hazardous Substances Data: 1418143-24-4(Hazardous Substances Data)

Upstream product

• 50586-62-4 diethyl cyanomethyl phosphonate 
• 1418142-65-0 4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexanone 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 1418143-11-9 3-(3-chlorophenyl)-N-(1,4-dioxaspiro[4.5]decan-8-yl)imidazo[1,2-b]pyridazin-6-amine 
• 97096-16-7 1,4-dioxaspiro[4.5]decan-8-amine 
• 131511-13-2 4-(N-benzylamino)cyclohexanone ethylene acetal 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 928336-86-1 6-chloro-3-(3-chlorophenyl)imidazo[1,2-b]pyridazine 
• 63503-60-6 3-chlorophenylboronic acid 
• 13526-66-4 3-bromo-6-chloro-imidazo[1,2-b]pyridazine 

Relevant articles and documents

Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.