14189-82-3

Usage

Uses

Used in Organic Synthesis:
3-(N-Phenyl-N-methyl)aminoacrolein is used as a key intermediate in organic synthesis for its ability to participate in various chemical reactions, facilitating the creation of complex organic molecules.
Used in Chemical Research:
In the field of chemical research, 3-(N-Phenyl-N-methyl)aminoacrolein is utilized as a model compound to study the reactivity of aminoacrolein derivatives and their potential applications in new chemical processes.
Used in Pharmaceutical Industry:
3-(N-Phenyl-N-methyl)aminoacrolein is used as a building block in the development of pharmaceutical compounds, leveraging its reactivity to form new drug candidates with potential therapeutic properties.
Used in Materials Science:
In materials science, 3-(N-Phenyl-N-methyl)aminoacrolein is employed as a component in the synthesis of novel materials, such as polymers and composites, that may exhibit unique properties due to the compound's reactive nature.
Used in Industrial Chemistry:
3-(N-Phenyl-N-methyl)aminoacrolein is utilized as a reactant in industrial chemical processes, where its reactivity can be harnessed to produce a variety of chemical products for different applications.

InChI:InChI=1/C10H11NO/c1-11(8-5-9-12)10-6-3-2-4-7-10/h2-9H,1H3

Upstream product

• 107-19-7 propargyl alcohol 
• 100-61-8 N-methylaniline 
• 624-67-9 Propargylic aldehyde 
• 122-31-6 malondialdehyde bis(diethyl acetal) 
• 111-34-2 -butyl vinyl ether 
• 93-61-8 N-methyl-N-phenylformamide 
• 107-02-8 acrolein 
• 102-52-3 malonaldehydebis(dimethylacetal) 

Downstream Products

• 93872-94-7 [4-(1,3,3-trimethyl-indolin-2-ylidene)-but-2-enylidene]-malononitrile 
• 289-95-2 PYRIMIDINE 
• 14371-10-9 (E)-3-phenylpropenal 
• 13466-40-5 (2E, 4E)-5-phenylpenta-2,4-dienal 
• 93957-50-7 3-<3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl>-2(E)-propenal 
• 57059-10-6 2-(furan-3-yl)pyrimidine 
• 27110-82-3 2-(furan-2-yl)pyrimidine 
• 100145-69-5 13-Methyl-11-phenyl-tricyclo[7.4.1.0^4,14]tetradeca-1⁽¹³⁾,2,4⁽¹⁴⁾,5,7,9,11-heptaene 
• 56578-35-9 4-methyl-cinnamaldehyde 
• 20432-35-3 3-(4-dimethylamino-phenyl)-propenal 
• 5362-56-1 4-methylpent-2-enal 
• 20884-05-3 (E)-3-(2-naphthyl)-2-propenal 
• 3913-81-3 (E)-2-decenal 
• 18829-56-6 (E)-2-Nonenal 

Relevant academic research and scientific papers

Cp2ZrCl2-catalyzed synthesis of 2-aminovinyl benzimidazoles under microwave conditions

A microwave-assisted general method for the synthesis of 2-aminovinyl benzimidazoles has been developed. Treatment of the 1,2-phenylenediamines and N-arylated/N,N-dialkylated 3-aminoacroleins with bis(cyclopentadienyl)zirconium(IV) dichloride (Cp2/s

Preparation method of 3-(N-methyl-N-phenyl)aminoacrolein

The invention relates to the technical field of pharmaceutical intermediates, in particular to a preparation method of 3-(N-methyl-N-phenyl)aminoacrolein. The preparation method comprises the following steps that tetramethoxypropane and N-methylaniline are put into a reaction flask, and after stirring is conducted for 10 min, diluted hydrochloric acid is dropwise added; after diluted hydrochloric acid is dropwise added completely, stirring is conducted for 2.5 h at the temperature of 24 DEG C to 26 DEG C; methylbenzene is added, and caustic soda liquid is dropwise added at 30 DEG C or below to regulate the pH value to be 6-7; standing is conducted for layering, a water layer is extracted with methylbenzene, organic layers are mixed, and washing is conducted three times with a saturated salt solution; standing is conducted for layering, a solvent in the organic layer is recycled by reducing pressure, 60-70-DEG C 40-mmHg distillates are collected, and then the product is obtained. According to the preparation method, expensive N-methylformanilide, n-butyl vinyl ether and propargyl alcohol are not used as raw materials, and therefore the cost is reduced; due to the fact that conventional solvents such as acetonitrile and chlorobenzene and poisonous substances such as triphosgene are not used, three waste pollution is reduced, and the reaction yield is increased; in the synthesis process, reacting is conducted at the environment temperature, the operation process is simplified, impurity generation is reduced, the quality of the product is improved, and the reaction yield is increased.

Synthetic method for N-substituent-3-aminoacrolein

The invention discloses a synthetic method for N-substituent-3-aminoacrolein. The method comprises the following steps: with secondary amine and 3-chloroallyl alcohol as raw materials, and active manganese dioxide as a catalyst, carrying out introducing into an air environment, then carrying out a reaction at 0.5 to 2.5 MPa and 40 to 90 DEG C for 6 to 14 h, and after completion of the reaction, postprocessing a reaction solution so as to obtain an N-substituent-3-aminoacrolein derivative, wherein the yield is 68% to 97%. Compared with a conventional method for synthesizing the N-substituent-3-aminoacrolein, the method provided by the invention has the advantages of low toxicity, low pollution, simple operation, etc.

Gold-catalyzed heterogeneous aerobic dehydrogenative amination of α,β-unsaturated aldehydes to enaminals

Although enaminals (β-enaminals) are very important compounds and have been utilized as useful synthons for various important compounds, they have been synthesized through non-green and/or limited procedures until now. Herein, we have successfully develop

Facile and highly enantioselective synthesis of (+)- and (-)-fluvastatin and their analogues

A highly enantioselective synthesis of (+)- and (-)-fluvastatin and their analogues has been facilitated by the reaction of an aldehyde with diketene in the presence of Ti(O-i-Pr)4 and a chiral Schiff base ligand. Either enantiomer of the Schiff base could be employed to obtain (+)- or (-)-fluvastatin. Diastereoselective reductions of the resultant keto moiety of β-hydroxy ketoesters provided the syn-1,3-diol esters (91% ee), which were subsequently recrystallized and saponified to afford (+)- and (-)-fluvastatin in >99.9% ee.

PROCESS FOR THE PREPARATION OF N-METHYL ANILINO ACROLEIN

This present invention relates to processes for the preparation of 3-N-methyl-N-phenylaminoacroline.

Azepinones. Part 1. Formation of simple 1H-azepin-3(2H)-ones by gas-phase pyrolysis: Crystal and molecular structure of 1-phenyl-1H-azepin-3(2H)-one

Flash vacuum pyrolysis of the Meldrum's acid derivatives (4) - (6) at 500 °C (10-3 Torr) gives good yields of the 1H-azepin-3(2H)-ones (7) - (9) respectively. X-Ray crystallography of the 1-phenylazepinone (8) shows that the dienaminone conjuga