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142034-76-2

2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 142034-76-2 Structure

  • Basic information

    1. Product Name: 2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide
    2. Synonyms: 2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide
    3. CAS NO:142034-76-2
    4. Molecular Formula:
    5. Molecular Weight: 191.658
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 142034-76-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide(142034-76-2)
    11. EPA Substance Registry System: 2-chloro-N-[trans-(1,2)-2-hydroxycyclohexyl]acetamide(142034-76-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 142034-76-2(Hazardous Substances Data)

142034-76-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 142034-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,0,3 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 142034-76:
(8*1)+(7*4)+(6*2)+(5*0)+(4*3)+(3*4)+(2*7)+(1*6)=92
92 % 10 = 2
So 142034-76-2 is a valid CAS Registry Number.

142034-76-2Relevant articles and documents

CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11 - BETA - HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF

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Paragraph 0450; 0451, (2015/06/17)

The present invention relates to certain amide derivatives that have the ability to inhibit 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.

A concise and efficient synthesis of substituted morpholines

Dugar, Sundeep,Sharma, Amit,Kuila, Bilash,Mahajan, Dinesh,Dwivedi, Sandeep,Tripathi, Vinayak

supporting information, (2015/02/19)

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11 - BETA - HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF

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Page/Page column 128, (2013/09/12)

The present invention relates to certain amide derivatives that have the ability to inhibit 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.

Chloroacetyl Group Migration in Cyclization of trans-N-Methyl-2-(chloroacetoxy)cyclohexylamine Hydrochloride

Katash, L. S.,Prishchepenko, V. M.,Zhavnerko, K. A.

, p. 831 - 833 (2007/10/03)

Cyclization of trans-N-methyl-2-(chloroacetoxy)cyclohexylamine under the action of alkali is preceded by O--> N migration of the chloroacetyl group with intermediate formation of corresponding chloroacetamide.

Preparation of diastereomerically pure immunologically active carbocyclic nor-muramyldipeptide analogues

Kikelj,Kidric,Pristovisek,Pecar,Urleb,Krbavcic,Honig

, p. 5915 - 5932 (2007/10/02)

The preparation of diastereomerically pure immunologically active carbocyclic nor-muramyldipeptide analogues (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-isoglutamine and (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-glutamic acid is described. The title compounds were synthesized using two independent synthetic routes from racemic trans-2-azidocyclohexanol and (1R,2R)-/(1S,2S)-2-aminocyclohexanol, respectively.

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