14214-31-4

Basic information

• Product Name: 2-chloro-3-isothiocyanato-prop-1-ene
• Synonyms: 2-chloro-3-isothiocyanato-prop-1-ene;2-chloro allyl isothiocyanate;2-Chloro-2-propenyl isothiocyanate;2-Chloro-3-isothiocyanatopropene
• CAS NO: 14214-31-4
• Molecular Formula: C₄H₄ClNS
• Molecular Weight: 133.6
• Mol File: 14214-31-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 182°C
• Flash Point: 63.9oC
• Appearance: /
• Density: 1.2700
• Vapor Pressure: 1.13mmHg at 25°C
• Refractive Index: 1.5560 (estimate)
• CAS DataBase Reference: 2-chloro-3-isothiocyanato-prop-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-isothiocyanato-prop-1-ene(14214-31-4)
• EPA Substance Registry System: 2-chloro-3-isothiocyanato-prop-1-ene(14214-31-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 14214-31-4(Hazardous Substances Data)

Usage

General Description

2-chloro-3-isothiocyanato-prop-1-ene is a chemical compound with the molecular formula C4H5ClNS. It is a clear, colorless liquid that is primarily used as an intermediate in the synthesis of organic chemicals. It is commonly employed in the production of pharmaceuticals, herbicides, and pesticides. 2-chloro-3-isothiocyanato-prop-1-ene has reactive properties and is known to be a potential irritant to the skin, eyes, and respiratory system. It is important to handle and store this chemical with caution to prevent any potential hazards.

InChI:InChI=1/C4H4ClNS/c1-4(5)2-6-3-7/h1-2H2

Upstream product

• 78-88-6 2,3-Dichloroprop-1-ene 
• 302-04-5 Thiocyanate 
• 333-20-0 potassium thioacyanate 
• 540-72-7 sodium thiocyanide 

Downstream Products

• 192723-46-9 (2-chloro-allyl)-dithiocarbamic acid benzyl ester 
• 105827-91-6 α-Cl-β-thiazolyl chloride 
• 122279-55-4 N-(2-chloro-allyl)-benzamide 

Relevant articles and documents

Tower reactor preparation 2 chloro -5 chloro - methylthiazole

The invention relates to the technical field 2 chlorine -5 chlorine - methylthiazole preparation, in particular to a tower reactor for preparing 2 chloro -5 chloro - methylthiazole, which comprises the following steps: S1. The sodium thiocyanate and the catalyst tetrabutylammonium bromide are added into the tower reactor, and then are metered into 2, 3 - dichloropropene and toluene respectively, stirred and heated to reflux. S2, followed by addition of tetrabutylammonium bromide, and isomerization reaction was performed after the temperature increase, and after completion of the reaction, negative pressure distillation was performed to obtain 2 - chloroallyl isothiocyanate. To the method, pollution to the environment can be reduced, hydrogen chloride gas generated in the reaction process can be reused, and the problem that the color of the product 2 chlorine -5 chlorine - methyl thiazole is too deep can be solved.

Thiamethoxam production method and extractant

The invention provides a thiamethoxam production method and an extractant, belongs to the technical field of pesticides, particularly provides an extractant taking ethylene glycol salicylate as a complexing agent, and also provides a composite extractant. The extractant comprises a complexing agent and a diluent, and the complexing agent comprises the ethylene glycol salicylate and P204, wherein the extraction ratio of ethylene glycol salicylate to P204 is 1:1.5 to 1:2. The ethylene glycol salicylate used as the complexing agent and -N- of thiamethoxam have strong ion association to generate an ion extract with the same structure, so that the distribution ratio is increased; and when the extractant and the P204 are used for composite extraction, hydrogen bond association of the strong electron withdrawing group nitro -NO2 of thiamethoxam and -OH of P204 can be promoted, and when the extraction ratio of ethylene glycol salicylate to the P204 extractant is 1:(1.5-2), the distribution ratio can be synergistically increased, and the extraction rate is increased.

Clean and environment-friendly production process of 2-chloro-5-chloromethylthiazole

The invention relates to a clean and environment-friendly production process of 2-chloro-5-chloromethylthiazole, which comprises the following steps: dissolving sodium thiocyanate in water, dropwiselyadding 2, 3-dichloropropene, carrying out heat preservation reaction after the dropwisely adding is completed, washing the obtained material with water, layering, and distilling to obtain an intermediate product 2-chloropropenyl isothiocyanate; dissolving the intermediate product in dichloroethane, dropwise adding sulfonyl chloride for the first time at the temperature of 30-60 DEG C, carrying out heat preservation reaction after dropwise adding is finished, degassing, desolventizing and cooling the obtained material, dropwise adding sulfonyl chloride for the second time, carrying out heat preservation reaction after dropwise adding for the second time, adding a stabilizer into the obtained material, and distilling to obtain 2-chloro-5-chloromethylthiazole. According to the invention, a pure byproduct sodium chloride is obtained, and the problem of high ammonia-nitrogen wastewater is solved. Due to the fact that the sulfonyl chloride is appropriate in use amount and is added in two times, by-products of sulfur dioxide and hydrogen chloride gas are reduced, the problem of environmental pollution is solved, and the production process is mild in reaction condition, small in toxicity,high in yield and purity and environmentally friendly.