1421688-63-2Relevant academic research and scientific papers
Discovering Novel α-aminoacyl-Containing Proline Derivatives with Potent and Selective Inhibitory Activity Against Dipeptidyl Peptidase IV: Design, Synthesis, Biological Evaluation, and Molecular Modeling
Zhang, Xiaodong,Wang, Jiang,Li, Zeng,Liu, Hong,Su, Mingbo,Li, Jingya,Li, Jia
, p. 843 - 852,10 (2012/12/12)
On the basis of the enzyme-binding features of known potent inhibitors of dipeptidyl peptidase IV, novel α-aminoacyl-containing proline analogs (8Aa-8Ak, 8Ba-8Bj, 8Ca-8Ck, and 8Da-8Di) with the S configuration were designed, synthesized, and their activit
