1421840-44-9

Usage

Uses

Used in Pharmaceutical Research:
(R)-N-(1-(5-chloro-2-hydroxyphenyl)ethyl)-4-methylbenzenesulfonamide is used as a potential drug candidate for its possible anti-inflammatory or antibacterial properties. Its unique structure positions it as a candidate for further research and development in the pharmaceutical industry, with the aim of identifying and optimizing its therapeutic applications.
Used in Medical Treatments:
As a potential drug candidate, (R)-N-(1-(5-chloro-2-hydroxyphenyl)ethyl)-4-methylbenzenesulfonamide may be utilized for the treatment of various medical conditions that could benefit from its anti-inflammatory or antibacterial effects. The specific applications would depend on the outcomes of ongoing research and clinical trials, which will provide insights into its safety, efficacy, and optimal use in medical treatments.
Further research and studies are essential to fully understand the potential uses and effects of (R)-N-(1-(5-chloro-2-hydroxyphenyl)ethyl)-4-methylbenzenesulfonamide, ensuring that it can be developed and applied responsibly and effectively in the medical field.

Upstream product

• 1421840-58-5 (R)-6-chloro-4-methyl-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 594-19-4 tert.-butyl lithium 
• 100-47-0 benzonitrile 
• 1228571-53-6 (R)-2-(1-aminoethyl)-4-chlorophenol 

Downstream Products

• 1421840-46-1 ((S)-4-chloro-2-[(1R)-1-{[(4-methylphenyl)sulfonyl]amino}ethyl]phenyl)-2-methoxyphenyl(phenyl)phosphinate 
• 1421840-47-2 (S)-4-chloro-2-[(1R)-1-{[(4-methylphenyl)sulfonyl]amino}ethyl]phenyl-2-(1,3-dioxolan-2-yl)phenyl(phenyl)phosphinate 
• 1421840-48-3 (S)-4-chloro-2-[(1R)-1-{[(4-methylphenyl)sulfonyl]amino}ethyl]phenylmesityl(phenyl)phosphinate 
• 1421840-49-4 (R)-4-chloro-2-((R)-1-(4-methylphenylsulfonamido)ethyl)phenyl tert-butyl(phenyl)phosphinate 
• 1421840-50-7 (S)-4-chloro-2-[(1R)-1-{[(4-methylphenyl)sulfonyl]amino}ethyl]phenyl-2',6'-dimethoxybiphenyl-2-yl(phenyl)phosphinate 
• 1421840-56-3 (2R,4R)-6-chloro-4-methyl-3-[(4-methylphenyl)sulfonyl]-2-(2,6-dimethoxy)phenyl-3,4-dihydro-2H-1,3,2-benzoxazaphosphinine 2-oxide 
• 1421840-45-0 C₂₁H₁₉ClNO₄PS 

Relevant academic research and scientific papers

Efficient asymmetric synthesis of structurally diverse p-stereogenic phosphinamides for catalyst design

The use of chiral phosphinamides is relatively unexplored because of the lack of a general method for the synthesis. Reported herein is the development of a general, efficient, and highly enantioselective method for the synthesis of structurally diverse P-stereogenic phosphinamides. The method relies on nucleophilic substitution of a chiral phosphinate derived from the versatile chiral phosphinyl transfer agent 1,3,2-benzoxazaphosphinine-2-oxide. These chiral phosphinamides were utilized for the first synthesis of readily tunable P-stereogenic Lewis base organocatalysts, which were used successfully for highly enantioselective catalysis.

Design and synthesis of chiral oxathiozinone scaffolds: Efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines

Is that S-O? The title scaffolds have a highly active and properly differentiated S-O bond for the efficient synthesis of enantiopure sulfinamides. The method is practical, green, and has the potential to provide an economical commercial process for the synthesis of bulky sulfinamides. Copyright

Efficient asymmetric synthesis of P -chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents

A general, efficient, and highly diastereoselective method for the synthesis of structurally and sterically diverse P-chiral phosphine oxides was developed. The method relies on sequential nucleophilic substitution on the versatile chiral phosphinyl transfer agent 1,3,2-benzoxazaphosphinine-2-oxide, which features enhanced and differentiated P-N and P-O bond reactivity toward nucleophiles. The reactivities of both bonds are fine-tuned to allow cleavage to occur even with sterically hindered nucleophiles under mild conditions.