1421923-96-7 Usage
Uses
Used in Pharmaceutical Industry:
(E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid is used as a key intermediate in the synthesis of various pharmaceuticals due to its high stability and the potential biological activities conferred by the 1H-1,2,4-triazole ring. Its resistance to metabolic degradation makes it an attractive component for the development of drugs with improved pharmacokinetic properties.
Used in Agrochemical Industry:
In the agrochemical industry, (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid is utilized as a building block for the creation of new crop protection products. (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid's stability and resistance to degradation contribute to the development of more effective and longer-lasting agrochemicals, enhancing their performance in protecting crops from pests and diseases.
Used in Medicinal Chemistry Research:
(E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid serves as a promising candidate for further research and development in the field of medicinal chemistry. Its unique structural features and potential biological activities make it an interesting subject for exploring new drug targets and developing innovative therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1421923-96-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,9,2 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1421923-96:
(9*1)+(8*4)+(7*2)+(6*1)+(5*9)+(4*2)+(3*3)+(2*9)+(1*6)=147
147 % 10 = 7
So 1421923-96-7 is a valid CAS Registry Number.
1421923-96-7Relevant articles and documents
PROCESS FOR PREPARING XPO1 INHIBITORS AND INTERMEDIATES FOR USE IN THE PREPARATION OF XP01 INHIBITORS
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Paragraph 0068; 0090-0091; 0093-0094, (2020/11/12)
The present invention provides an improved process for preparation of the (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid (referred to as compound of the structural formula (III)), which is a useful key intermediate for the sy
HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF
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, (2013/03/26)
The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
