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142217-77-4

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  • High quality (1S,2R,3S,5S)-5-(2-Amino-6-(Benzyloxy)-9H-Purin-9-Yl)-3-(Benzyloxy)-2-(Benzyloxymethyl)Cyclopentanol? supplier in China

    Cas No: 142217-77-4

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  • (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol, Entecavir Intermediate 142217-77-4

    Cas No: 142217-77-4

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  • [1S-(1α,2β,3α,5β)]-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)-methyl]-cyclopentanol

    Cas No: 142217-77-4

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  • (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol/ LIDE PHARMA- Factory supply / Best price

    Cas No: 142217-77-4

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142217-77-4 Usage

General Description

The chemical (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol is a complex compound with a purine base and multiple benzyl group attachments. It is a cyclopentanol derivative with a purine moiety incorporating an amino group and multiple benzyloxy groups. The presence of these functional groups indicates that the compound may have potential biological activity, possibly interacting with purine receptors or enzymes involved in purine metabolism. The multiple benzyl group attachments also suggest that this compound may have some degree of lipophilicity, potentially affecting its pharmacokinetics and tissue distribution. Further research and investigation are needed to fully understand the chemical and biological properties of this complex molecule.

Check Digit Verification of cas no

The CAS Registry Mumber 142217-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,2,1 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 142217-77:
(8*1)+(7*4)+(6*2)+(5*2)+(4*1)+(3*7)+(2*7)+(1*7)=104
104 % 10 = 4
So 142217-77-4 is a valid CAS Registry Number.
InChI:InChI=1/C32H33N5O4/c33-32-35-30-28(31(36-32)41-19-24-14-8-3-9-15-24)34-21-37(30)26-16-27(40-18-23-12-6-2-7-13-23)25(29(26)38)20-39-17-22-10-4-1-5-11-22/h1-15,21,25-27,29,38H,16-20H2,(H2,33,35,36)/t25-,26+,27+,29+/m1/s1

142217-77-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

1.2 Other means of identification

Product number -
Other names (1S,2S,3S,5S)-5-(2-amino-6-phenylmethoxypurin-9-yl)-3-phenylmethoxy-2-(phenylmethoxymethyl)cyclopentan-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:142217-77-4 SDS

142217-77-4Relevant articles and documents

Method for synthesizing Entecavir intermediate

-

Paragraph 0031-0034, (2020/03/05)

The invention relates to a method for synthesizing an Entecavir intermediate and particularly relates to a method for synthesizing a compound represented by a formula I. According to the method, firstly, amino of 6-benzyloxy guanine is protected, and thus

BMS-200475, a novel carbocyclic 2'-deoxyguanosine analog with potent and selective anti-hepatitis B virus activity in vitro

Bisacchi,Chao,Bachard,Daris,Innaimo,Jacobs,Kocy,Lapointe,Martel,Merchant,Slusarchyk,Sundeen,Young,Colonno,Zahler

, p. 127 - 132 (2007/10/03)

BMS-200475, a never carbocyclic analog of 2'-deoxyguanosine, is a potent inhibitor of hepatitis B virus in vitro (ED50 = 3 nM) with relatively low cytotoxicity (CC50 = 21-120 μM). A practical 10-step asymmetric synthesis was developed affording BMS-200475 in 18% overall chemical yield and > 99% optical purity. The enantiomer of BMS-200475 as well as the adenine, thymine, and iodouracil analogs are much less active.

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