142226-16-2

Upstream product

• 115693-78-2 1,2:5,6-di-O-isopropylidene-3-O-(4-methoxybenzyl)-α-D-glucofuranose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 329899-60-7 (3aR,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 105-13-5 4-Methoxybenzyl alcohol 
• 824-94-2 p-methoxybenzyl chloride 
• 14686-89-6 (1,2:5,6)-di-O-isopropylidene-D-gulose 
• 2595-05-3 Diacetone D-glucose 
• 69940-02-9 3-O-(4-Methoxybenzyl)-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 329899-64-1 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 

Downstream Products

• 82529-87-1 (3aR,5S,6S,6aR)-6-(4-methoxybenzyloxy)-tetrahydro-2,2-dimethylfuro[2,3-d][1,3]dioxole-5-carbaldehyde 
• 82530-09-4 1,2-O-isopropylidene-3-O-(4-methoxybenzyl)-6-O-(p-tolylsulfonyl)-α-D-glucofuranose 
• 199458-24-7 Toluene-4-sulfonic acid (R)-2-hydroxy-2-[(3aR,5R,6R,6aR)-6-(4-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethyl ester 
• 205934-52-7 1,2-O-isopropylidene-5,6-di-O-methanesulfonyl-3-O-(4-methoxybenzyl)-α-D-allofuranose 
• 500187-80-4 (1R,2R,3R,4R)-3-(4-Methoxy-benzyloxy)-1-prop-1-ynyl-4-vinyl-cyclobutane-1,2-diol 
• 500187-81-5 (1R,2R,3R,4R)-3-(4-Methoxy-benzyloxy)-1-phenylethynyl-4-vinyl-cyclobutane-1,2-diol 
• 500187-77-9 (1R,2R,3R,4R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-1-prop-1-ynyl-4-vinyl-cyclobutanol 
• 500187-78-0 (1R,2R,3R,4R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-1-phenylethynyl-4-vinyl-cyclobutanol 
• 205934-53-8 (3aR,5R,6R,6aR)-6-(4-methoxybenzyloxy)-2,2-dimethyl-5-vinyltetrahydrofuro[2,3-d][1,3]dioxole 
• 500187-74-6 (2R,3R,4S,5R)-2-Methoxy-4-(4-methoxy-benzyloxy)-5-vinyl-tetrahydro-furan-3-ol 
• 500187-75-7 (1R,2S,3R,4S)-3-(4-methoxybenzyloxy)-2-((tert-butyl)dimethylsilyloxy)-4-vinylcyclobutanol 
• 500187-72-4 tert-Butyl-[(2R,3R,4R,5R)-2-methoxy-4-(4-methoxy-benzyloxy)-5-vinyl-tetrahydro-furan-3-yloxy]-dimethyl-silane 
• 500187-71-3 tert-Butyl-[(2S,3R,4R,5R)-2-methoxy-4-(4-methoxy-benzyloxy)-5-vinyl-tetrahydro-furan-3-yloxy]-dimethyl-silane 

Relevant academic research and scientific papers

Ceric ammonium nitrate/pyridine: A mild reagent for the selective deprotection of cyclic acetals and ketals in the presence of acid labile protecting groups

The reagent system ceric ammonium nitrate/pyridine can perform the cleavage of primary and (in some cases) secondary acetonides, benzylidenes and tetrahydropyranyl ethers. The mild acididity of the reaction system (pH 4.4) allows deprotections to be performed in the presence of several acid labile protecting groups.

Synthesis of (+)-altholactone, (+)-7-epi-altholactone, (?)-etharvensin, and (+)-alumheptolide-A using Pd-catalyzed carbonylation

Syntheses of (+)-altholactone isolated from Goniothalamus giganteus and its C-7 epimer (+)-7-epi-altholactone, (?)-etharvensin and (+)-alumheptolide-A were achieved. The lactone ring of these compounds was constructed using Pd-catalyzed carbonylation.

ADENINE DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND PRODUCTION METHOD AND USE OF THE SAME

PROBLEM TO BE SOLVED: To provide an adenine derivative represented by general formula (I) or a pharmacologically acceptable salt thereof. SOLUTION: This invention provides an adenine derivative represented by general formula (I) or a pharmacologically acc

Ultrasound-assisted selective deprotection of terminal acetonides catalyzed by silica-supported boron trifluoride

An efficient and convenient method for the selective cleavage of terminal acetonides is described. Treatment of terminal acetonides in the presence of a wide range of functional groups with silica-supported boron trifluoride as a catalyst furnished the corresponding diols in 82-95% yield under ultrasound irradiation conditions. The acid-labile p-methoxybenzyl group as a protecting group remained intact under the conditions employed to the present deprotection condition. Copyright Taylor & Francis Group, LLC.

Total synthesis of macrosphelide M from diacetone glucose

The total synthesis of macrosphelide M is described. The key steps include the preparation of the acid and alcohol fragments from diacetone glucose and (S)-malic acid, respectively, followed by Yamaguchi esterification and macrocyclization of the tris-olefin by ring-closing metathesis. Finally, one-pot deprotection of the PMB and TBS groups with TiCl4 results in the target. The C-3/C-4 stereocenters of diacetone glucose are used for the introduction of four stereocenters, whereas the fifth stereocenter is realized from (S)-malic acid. The total synthesis of macrosphelide M was achieved from diacetone glucose and (S)-malic acid. The key steps include Yamaguchi esterification and macrocyclization of the tris-olefin by the second-generation Grubbs catalyst.

Synthesis of imidazo[2,1-b]thiazoles linked to an unprotected carbohydrate moiety

Two series of imidazo[2,1-b]thiazoles substituted on C-3 or C-5 with an unprotected carbohydrate moiety were synthesized. Different protective groups for position 3 of the carbohydrate moiety were tested (acetyl, tert-butyldimethylsilyl (TBDMS), and p-met

Thieme chemistry journal awardees - Where are they now? Approaches to tagetitoxin and its decarboxy analogue from d -glucose

A fifteen-step route has been developed from 1,6-anhydro-β-d- glucopyranose to a C-alkynyl glycoside precursor of decarboxytagetitoxin. Preparation of 1,6-anhydro-5-C-vinyl-β-d-gluco-pyranose, a potential precursor of tagetitoxin, is also described. Georg

Synthesis of pyrenolide D analogues

We present a short, enantiospecific synthesis of four hydroxylated analogues of pyrenolide D from D-glucose based on furan oxidative spirocyclisation. Georg Thieme Verlag Stuttgart.

Sulfuric acid immobilized on silica: an efficient reusable catalyst for selective hydrolysis of the terminal O-isopropylidene group of sugar derivatives

Sulfuric acid immobilized on silica proved to be an efficient catalyst for selective hydrolysis of the terminal O-isopropylidene group of sugar derivatives. The method is very simple and economic for large-scale synthesis in which the catalyst is recovered and reused for several runs. Reactions with di-O-isopropylidene derivatives of d-glucose, d-mannose, d-fructose and l-sorbose led to the formation of the corresponding mono-O-isopropylidene derivatives in good to excellent yields.

Phosphomolybdic acid supported on silica gel: An efficient, mild and reusable catalyst for the chemoselective hydrolysis of acetonides

Carbohydrate acetonides were chemoselectively cleaved to the corresponding diols by using environmentally benign phosphomolybdic acid (H 3PMo12O40) supported on silica gel (PMA-SiO2) at ambient temperature in a