14229-93-7 Usage
Uses
Used in Pharmaceutical Research:
2,4-Diphenyl-5-methylthiazole is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its potential biological and pharmacological properties. Its unique structural features enable the development of new drugs with improved therapeutic effects and reduced side effects.
Used in Agrochemical Development:
In the agrochemical industry, 2,4-diphenyl-5-methylthiazole is used as a building block for the creation of novel agrochemicals with enhanced efficacy and selectivity. Its structural features allow for the design of compounds with improved pest control and resistance management properties.
Used in Antimicrobial Applications:
2,4-Diphenyl-5-methylthiazole is employed as an antimicrobial agent, exhibiting activity against a wide range of bacteria. Its unique chemical structure allows it to disrupt bacterial cell membranes and inhibit essential cellular processes, making it a promising candidate for the development of new antimicrobial agents to combat drug-resistant infections.
Used in Antifungal Applications:
In the field of antifungal research, 2,4-diphenyl-5-methylthiazole is used as a potential antifungal agent, showing activity against various fungal species. Its ability to interfere with fungal cell wall synthesis and other essential processes makes it a valuable compound for the development of new antifungal drugs to treat fungal infections.
Used in Antioxidant Formulations:
2,4-Diphenyl-5-methylthiazole is utilized as an antioxidant in various industrial applications, including food preservation, cosmetics, and pharmaceuticals. Its ability to scavenge free radicals and protect against oxidative stress makes it a valuable component in antioxidant formulations, helping to extend the shelf life of products and maintain their quality.
Check Digit Verification of cas no
The CAS Registry Mumber 14229-93-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,2 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14229-93:
(7*1)+(6*4)+(5*2)+(4*2)+(3*9)+(2*9)+(1*3)=97
97 % 10 = 7
So 14229-93-7 is a valid CAS Registry Number.
14229-93-7Relevant academic research and scientific papers
Four-component thiazole formation from simple chemicals under metal-free conditions
Jiang, Jingjing,Huang, Huawen,Deng, Guo-Jun
supporting information, p. 986 - 990 (2019/03/12)
Multi-component reactions for the synthesis of polysubstituted thiazoles from simple chemicals are described. Under metal-free reaction conditions, cheap and easily available ketones, aldehydes, ammonium salt, and elemental sulfur are self-assembled to provide entries to three thiazoles in moderate to good yield with a range of functionalities tolerated.
Exploration and Optimization of an Efficient One-pot Sequential Synthesis of Di/tri-substituted Thiazoles from α-Bromoketones, Thioacids Salt, and Ammonium Acetate
Venkateswararao, Eeda,Jalani, Hitesh B.,Manoj,, Manickam,Jung, Sang-Hun
supporting information, p. 1449 - 1456 (2016/09/24)
Exploration of scope of an optimized one-pot sequential procedure for preparing of 2,4-di- and 2,4,5-tri-substituted thiazoles has been accomplished. The synthesis was performed by the initial formation of a β-keto-thioester intermediate from nucleophilic substitution of α-bromoketones with thioacid potassium salts, followed by treatment with ammonium acetate and one equivalent of acetic acid in toluene to form imine intermediate eventually leading to cyclization yielding thiazoles. This procedure should be highlighted with a flexible way to control the substitution pattern around thiazole ring by choosing appropriately substituted α-bromoketones even containing acid labile functionality and thioacid potassium salts, and thus its applicability is very wide.
One pot synthesis of substituted imidazopyridines and thiazoles from styrenes in water assisted by NBS
Shinde, Mahesh H.,Kshirsagar, Umesh A.
, p. 1455 - 1458 (2016/04/04)
Heating of commercially available styrenes with NBS in water followed by reaction with 2-aminopyridines or thioamides afforded important heterocyclic scaffolds in a one pot procedure. The reaction proceeds via co-oxidant free, in situ formation of α-bromoketone using NBS as a bromine source as well as an oxidant followed by trapping with suitable nucleophiles to provide imidazopyridines and thiazoles.
