1424-66-4

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-(dimethylamino)benzaldehyde is used as a key intermediate in the synthesis of arylidenaminoguanidine derivatives, which possess antihypertensive activity. These derivatives are valuable in the development of medications aimed at treating hypertension, a prevalent medical condition characterized by high blood pressure.
Additionally, due to its reactivity and structural features, 2-chloro-4-(dimethylamino)benzaldehyde can be employed in the development of other pharmaceutical compounds, potentially expanding its applications in the pharmaceutical industry.

InChI:InChI=1/C9H10ClNO/c1-11(2)8-4-3-7(6-12)9(10)5-8/h3-6H,1-2H3

Upstream product

• 50-00-0 formaldehyd 
• 6848-13-1 3-chloro-N,N-dimethylaniline 
• 302-17-0 chloral hydrate 

Downstream Products

• 38299-31-9 (2-chloro-4-dimethylamino-benzylidene)-malononitrile 
• 20172-75-2 {3-Chloro-4-[(E)-dodecyliminomethyl]-phenyl}-dimethyl-amine 
• 87539-66-0 {3-Chloro-4-[(4-chloro-phthalazin-1-yl)-hydrazonomethyl]-phenyl}-dimethyl-amine 
• 87539-66-0 (3-Chloro-4-{[4-chloro-2H-phthalazin-(1Z)-ylidene]-hydrazonomethyl}-phenyl)-dimethyl-amine 
• 87540-10-1 [3-Chloro-4-(6-pyrrolidin-1-yl-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-phenyl]-dimethyl-amine 
• 959407-25-1 (5Z)-3-(4-bromobenzyl)-5-(2-chloro-4-dimethylaminobenzylidene)-5H-furan-2-one 
• 1034864-57-7 2-chloro-4-dimethylamino-1-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)benzene 
• 118630-46-9 C₁₆H₂₂ClN₅S 
• 118630-32-3 1-<2-Chloro-4-(dimethylamino)benzyl>piperazine 
• 87540-50-9 [3-Chloro-4-(6-ethoxy-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-phenyl]-dimethyl-amine 
• 113628-55-0 [3-Chloro-4-(6-chloro-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-phenyl]-dimethyl-amine 

Relevant academic research and scientific papers

Process for nucleophilic fluoroalkylation of aldehydes

Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

Novel compounds, processes and marking systems

Mono and bis substituted (arylsulfonyl)alkanes useful as color formers, particularly in carbonless duplicating and thermal marking systems, are prepared by the interaction of the appropriate aldehyde or dialdehyde with the appropriate aryl or heterocyclic moiety and the appropriate phenylsulfinic acid in the presence of a catalyst.