1424371-49-2

Basic information

• Product Name: C₁₆H₂₂O₂
• Synonyms: C₁₆H₂₂O₂
• CAS NO: 1424371-49-2
• Molecular Weight: 246.349
• Mol File: 1424371-49-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₂O₂(1424371-49-2)
• EPA Substance Registry System: C₁₆H₂₂O₂(1424371-49-2)

Safety Data

• Hazardous Substances Data: 1424371-49-2(Hazardous Substances Data)

Upstream product

• 1589590-44-2 C₁₆H₂₄O₂ 
• 626-20-0 3-methoxystyrene 
• 93782-92-4 (E)-6-iodo-5-methylhex-5-en-1-ol 
• 1424371-41-4 (E)-8-(3-methoxyphenyl)-5-methyloct-5-enenitrile 
• 1424371-40-3 (E)-7-(3-methoxyphenyl)-4-methylhept-4-en-1-ol 
• 54247-08-4 5-(3-methoxyphenyl)-2-methylpent-1-en-3-ol 
• 40138-66-7 3-(m-methoxyphenyl)propanal 
• 1424371-48-1 C₁₇H₂₄O₃ 
• 50704-52-4 methyl 3-(3-methoxyphenyl)propionate 
• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 

Downstream Products

• 1424371-42-5 (4R,5R)-2-((E)-7-(3-methoxyphenyl)-4-methylhept-4-enyl)-4,5-dimethyl-1,3-dioxolane 
• 1589590-99-7 C₁₇H₂₆O₂ 
• 76280-80-3 (1S,4aR,10aS)-7-Methoxy-4a-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-ol 
• 76280-80-3 (1R,4aR,10aS)-7-Methoxy-4a-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-ol 
• 469-83-0 (+/-)-cafestol 

Relevant articles and documents

Total synthesis of (±)-cafestol: A late-stage construction of the furan ring inspired by a biosynthesis strategy

An efficient bioinspired approach to the total synthesis of (±)-cafestol features a late-stage installation of the furan ring with a mild Au-catalyzed cycloisomerization. The Et2AlCl-promoted aldehyde-ene cyclization and subsequent Friedel-Crafts reaction deliver a requisite tricyclic system in gram scale with high stereo- and regioselectivity. Moreover, a highly stereoselective SmI2-mediated aldehyde-alkene radical cyclization furnishes the key bicyclo[3.2.1]octane skeleton to offer an advanced intermediate for the synthesis of other oxygenated ent-kaurene diterpenoids.