142508-07-4

Usage

Uses

Used in Pharmaceutical Industry:
(1S,2R)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL is used as a chiral building block for the creation of pharmaceuticals and other biologically active molecules. Its chiral nature makes it especially useful in the creation of enantiomerically pure pharmaceuticals.
Used in Medicinal Chemistry:
(1S,2R)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL is used as a chiral building block in the development of new drugs and bioactive compounds. The isopropylamino group is a common substituent in many drugs and bioactive compounds, making it a valuable component in medicinal chemistry.
Used in Organic Synthesis:
(1S,2R)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL is used as a chiral building block in organic synthesis, allowing for the creation of a wide range of enantiomerically pure compounds.
Used in Pharmacological Research:
(1S,2R)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL is studied for its potential pharmacological properties, such as analgesic and anticancer effects, making it a promising candidate for further research and development in the field of medicine.

InChI:InChI=1/C17H21NO/c1-13(2)18-16(14-9-5-3-6-10-14)17(19)15-11-7-4-8-12-15/h3-13,16-19H,1-2H3/t16-,17+/m1/s1

Upstream product

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 67-64-1 acetone 
• 142452-46-8 (4R,5S)-2,2-Dimethyl-4,5-diphenyl-oxazolidine 
• 54810-54-7 2-(N-isopropylamino)-2-phenylacetonitrile 
• 100-52-7 benzaldehyde 

Downstream Products

• 142464-97-9 (1S,2R)-1-benzyloxy-2-isopropylamino-1,2-diphenylethane 

Relevant academic research and scientific papers

One-pot synthesis of trisubstituted 1,2-amino alcohols from deprotonated α-amino nitriles

A short synthesis of N,1,2-trisubstituted vicinal amino alcohols by 1,2-addition of deprotonated N-monosubstituted α-amino nitriles to aldehydes and subsequent one-pot reduction of the intermediates with borane-THF is described. This procedure leads to the predominant formation of the anti-configured products. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

Asymmetric synthesis XVII. New chiral catalysts for the stereocontrolled addition of benzaldehyde by diethylzinc

Enantioselective addition of benzaldehyde with diethylzinc catalyzed by a few classes of new chiral ligands (3a-3h) and their structural relations are disclosed herein. The stereocontrolled syntheses of both (S)- and (R)-1-phenyl-1-propanol are achieved i

Facile Preparation of Some Highly Hindered Chiral 1,2-Diphenyl-2-(N-monoalkyl)amino Alcohols and N-Benzylbornamine

The preparation of some novel chiral 1,2-diphenyl-2-(N-monoalkyl)amino alcohols by a facile one-pot procedure and the synthesis of N-benzylbornamine by a reduction process are described herein.

Studies on reaction conditions and new entry to chiral ligands in the chiral lithium amide-mediated enantioselective aldol reaction

Reaction conditions for the enantioselective aldol reaction of 2,2-dimethyl-3-pentanone (3) and benzaldehyde using the chiral lithium amide 1b as a chiral auxiliary were thoroughly investigated. All three procedures, that is, (1) the combined use of lithi