1426-70-6

Usage

Explanation

These are alternative names for the compound, which are used to describe its structure and properties.

Explanation

A ketone is a type of organic compound that contains a carbonyl group (C=O) bonded to two other carbon atoms. In this case, the carbonyl group is attached to a six-carbon chain and a fluorine-substituted phenyl group.

Explanation

The compound has a linear chain of six carbon atoms, with the first carbon atom bonded to a phenyl group (a six-membered aromatic ring) that has a fluorine atom as a substituent.

Explanation

1-Hexanone, 1-(4-fluorophenyl)is used in the synthesis of various pharmaceuticals and can also act as a solvent in different chemical reactions and processes due to its ability to dissolve a wide range of substances.

Explanation

As with any chemical compound, it is essential to follow proper handling and safety procedures when working with 1-Hexanone, 1-(4-fluorophenyl)to minimize the risk of accidents or exposure to hazardous conditions. This may include wearing personal protective equipment (PPE), working in a well-ventilated area, and following specific guidelines for storage and disposal.

Chemical Class

Ketone

Structure

Six-carbon chain with a fluorine-substituted phenyl group at the first carbon

Applications

Pharmaceutical production, solvent in chemical reactions and processes

Additional Applications

Organic synthesis and research

Safety Measures

Proper handling and precautions required

Upstream product

• 462-06-6 fluorobenzene 
• 142-61-0 Hexanoyl chloride 
• 188245-43-4 1-fluoro-4-(n-butylethynyl)benzene 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 71-36-3 butan-1-ol 
• 66-25-1 hexanal 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 693-25-4 n-pentylmagnesium bromide 
• 1283075-99-9 dipropan-2-yl 1-(4-fluorobenzoyl)hydrazine-1,2-dicarboxylate 
• 88070-48-8 N-methylbenzamide 
• 459-57-4 4-fluorobenzaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 1496-36-2 1-(4-fluorophenyl)cyclohexan-1-ol 
• 850132-22-8 N-(1-(3-methylpyridin-2-ylamino)hexyl)-3-methylpyridin-2-amine 

Downstream Products

• 2728-88-3 α-<4-Fluor-phenyl>-hexylamin 

Relevant academic research and scientific papers

Preparation method of aryl ketone compound

The invention provides a preparation method of an aryl ketone compound, and belongs to the technical field of compound synthesis. The method comprises the following steps: under the action of a silver catalyst and water, carrying out reaction on aryl alkyne with a structure as shown in a formula 1 in a solvent at 60-120 DEG C for 12-48 hours, and separating and purifying a product after the reaction is finished, so as to obtain the single aryl ketone compound with a structure as shown in a formula I, the raw materials are easy to obtain, the experimental operation is simple, the yield of the prepared single aryl ketone compound is good, and gram-scale experiments can be carried out.

Iron-Catalyzed C-C Single-Bond Cleavage of Alcohols

An iron-catalyzed deconstruction/hydrogenation reaction of alcohols through C-C bond cleavage is developed through photocatalysis, to produce ketones or aldehydes as the products. Tertiary, secondary, and primary alcohols bearing a wide range of substituents are suitable substrates. Complex natural alcohols can also perform the transformation selectively. A investigation of the mechanism reveals a procedure that involves chlorine radical improved O-H homolysis, with the assistance of 2,4,6-collidine.

Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones

In this communication we describe a novel strategy for the formation of valuable diaryl and aryl alkyl ketones from acyl hydrazides. A wide variety of ketones are prepared and the mild reaction conditions allow for the use of a range of functionalities, especially in the synthesis of diaryl ketones.

Direct acylation of aryl bromides with aldehydes by palladium catalysis

A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis, affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner, and broadening the scope of metal-catalyzed coupling reactions. Copyright

Ir- and Ru-catalyzed sequential reactions: Asymmetric α-alkylative reduction of ketones with alcohols

(Chemical Equation Presented) The compatibility between [{IrCl(cod)} 2] and ruthenium complex 1 to achieve asymmetric α-alkylative reduction of prochiral ketones with primary alcohols is an essential factor in obtaining optically active alcohols with elongation of the carbon skeleton in good yields with a high enantioselectivity.

Ruthenium-catalyzed coupling of aldimines with arylboronates: New synthetic method for aromatic ketones

Using the chelation strategy, the reaction of aldimines bearing the 3-picolin-2-yl group with various arylboronates in the presence of a ruthenium catalyst furnished the corresponding ketimines in high yields for a short reaction time; the resulting ketimines were readily converted to ketones by hydrolysis. The Royal Society of Chemistry 2005.

Palladium-catalyzed intermolecular hydroamination of alkynes: A dramatic rate-enhancement effect of o-aminophenol

The hydroamination of alkynes using o-aminophenol proceeds in very high to good yields in the presence of Pd(NO3)2 catalyst. Remarkable rate enhancement with o-aminophenol is presumably due to the chelation effect of the ortho OH group to palladium. Copyright