142646-11-5

Basic information

• Product Name: Carbamic acid, [[[2-nitro-4-(phenylmethoxy)phenyl]amino]thioxomethyl]-, ethyl ester
• CAS NO: 142646-11-5
• Molecular Formula: C17H17N3O5S
• Molecular Weight: 375.405
• Mol File: 142646-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[[2-nitro-4-(phenylmethoxy)phenyl]amino]thioxomethyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[[2-nitro-4-(phenylmethoxy)phenyl]amino]thioxomethyl]-, ethyl ester(142646-11-5)
• EPA Substance Registry System: Carbamic acid, [[[2-nitro-4-(phenylmethoxy)phenyl]amino]thioxomethyl]-, ethyl ester(142646-11-5)

Safety Data

• Hazardous Substances Data: 142646-11-5(Hazardous Substances Data)

Upstream product

• 16182-04-0 Ethoxycarbonyl isothiocyanate 
• 26697-34-7 N-(4-(benzyloxy)-2-nitrophenyl)acetamide 
• 103-90-2 4-acetaminophenol 

Relevant articles and documents

Synthesis, antineoplastic and anthelmintic activities of N-alkyloxycarbonyl-N'-(4-benzyloxy-2-nitrophenyl)thioureas as prodrugs of (6-benzyloxy-1H-benzimidazol-2-yl)carbamic acid ester

N-Methoxycarbonyl-N'-(4-benzyloxy-2-nitrophenyl)thiourea (7) has been synthesised as a potential prodrug of (6-benzyloxy-1H-benzimidazol-2-yl)carbamic acid methyl ester (9).Biological activities of the compounds 7-10 have been evaluated against Ehrlich ascites carcinoma, ascaris and hymenolepis infected animals.Ethyl carbamates (8,10) show poor activity and compounds 7 and 9 are well tolerated in acute toxicity study.The intestinal bacterial flora E. coli can cyclise the compound 7 to 9.