26697-34-7

Usage

InChI:InChI=1/C15H14N2O4/c1-11(18)16-14-8-7-13(9-15(14)17(19)20)21-10-12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,16,18)

Upstream product

• 41927-14-4 N-[4-(benzyloxy)phenyl]acetamide 
• 7403-75-0 N-(4-hydroxy-2-nitrophenyl)-acetamide 
• 100-39-0 benzyl bromide 
• 103-84-4 Acetanilid 
• 100-51-6 benzyl alcohol 
• 100-44-7 benzyl chloride 
• 103-90-2 4-acetaminophenol 

Downstream Products

• 142646-11-5 C₁₇H₁₇N₃O₅S 
• 142646-10-4 N-methoxycarbonyl-N'-(4-benzyloxy-2-nitrophenyl)thiourea 
• 54029-21-9 (6-benzyloxy-1H-benzimidazol-2-yl)carbamic acid methyl ester 
• 26697-35-8 4-benzyloxy-2-nitroaniline 

Relevant academic research and scientific papers

Acylamino-Directed Specific Sequential Difunctionalizations of Anilides via Metal-Free Relay Reactions for p-Oxygen and o-Nitrogen Incorporation

Novel acylamino-directed relay disubstitutions realize the sequential difunctionalizations of anilides (1) under mild and metal-free conditions for the first time. This [bis(trifluoroacetoxy)iodo]benzene (PIFA) and BF3·Et2O promoted straightforward reaction produces a series of p-acetoxyl- or p-alkoxyl-o-nitro-N-arylamides (2), which are key scaffolds of various drugs, functional materials, and bioactive molecules. The flexibility with respect to the functional groups in these products affords this novel protocol excellent versatility for synthetic applications.

Disperse scarlet dye compound, preparation method therefor and application of disperse scarlet dye compound

The invention discloses a disperse scarlet dye compound, a preparation method therefor and an application of the disperse scarlet dye compound. The disperse scarlet dye compound has a structure represented by a formula (I) shown in the description, wherein R is alkyl, alkoxy, halogen, nitro, cyano, a formula shown in the description or -OCH2CH=CH2. The invention provides the application of the disperse scarlet dye compound in printing and dyeing of hydrophobic textile materials. The disperse scarlet dye compound is bright-colored and beautiful in color and luster and has excellent washing fastness and sublimation fastness.

Functionalized alkoxy arene diazonium salts from paracetamol

Arene diazonium tetrafluoroborates can be synthesized from aromatic acetamides via a sequence of deacetylation, diazotation and precipitation, induced by anion exchange. The reaction is conducted as a convenient one-flask transformation with consecutive addition of the appropriate reagents. Exchange of solvents or removal of byproducts prior to isolation of the product is not required. The arene diazonium salts are isolated from the reaction mixture by simple filtration. Two complementary protocols are presented, and the utility of the reaction is exemplified for a synthesis of the diarylheptanoid natural product de-O-methyl centrolobine.

Synthesis, antineoplastic and anthelmintic activities of N-alkyloxycarbonyl-N'-(4-benzyloxy-2-nitrophenyl)thioureas as prodrugs of (6-benzyloxy-1H-benzimidazol-2-yl)carbamic acid ester

N-Methoxycarbonyl-N'-(4-benzyloxy-2-nitrophenyl)thiourea (7) has been synthesised as a potential prodrug of (6-benzyloxy-1H-benzimidazol-2-yl)carbamic acid methyl ester (9).Biological activities of the compounds 7-10 have been evaluated against Ehrlich ascites carcinoma, ascaris and hymenolepis infected animals.Ethyl carbamates (8,10) show poor activity and compounds 7 and 9 are well tolerated in acute toxicity study.The intestinal bacterial flora E. coli can cyclise the compound 7 to 9.

5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Carbalkoxythioureidobenzene derivatives represented by the following formula: STR1 where R is a lower alkyl group having 1 to 4 carbon atoms; R1 is --SR2, --SOR2, --SO2 R2, --OR2, --SCN, --SC(O)NR3 R4, or --M'(CH2)n MR7 where n is 1-4; R2 is lower alkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, lower alkenyl or lower alkynyl having 3 to 6 carbon atoms, aralkyl or aryl, provided that when R1 is --SO2 R2, R2 is not aralkyl or phenyl; R3 and R4 are independently hydrogen or lower alkyl having 1 to 6 carbon atoms; Y is amino, nitro, acylamino where the acyl portion has 1 to 6 carbon atoms, --NHC(O) (CH2)m COOH where m is 1-6, or --NHC(S)NHCOOR; M and M' are independently O, S or STR2 and R7 is lower alkyl having 1 to 4 carbon atoms or aryl. The R1 substitution is either at the 4- or 5-position. The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents.