1426814-56-3

Basic information

• Product Name: (R)-methyl 2-bromo-3-(4-fluorophenyl)propanoate
• Synonyms: (R)-methyl 2-bromo-3-(4-fluorophenyl)propanoate
• CAS NO: 1426814-56-3
• Molecular Weight: 261.091
• Mol File: 1426814-56-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-methyl 2-bromo-3-(4-fluorophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-methyl 2-bromo-3-(4-fluorophenyl)propanoate(1426814-56-3)
• EPA Substance Registry System: (R)-methyl 2-bromo-3-(4-fluorophenyl)propanoate(1426814-56-3)

Safety Data

• Hazardous Substances Data: 1426814-56-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1426814-68-7 (2R)-2-bromo-3-(4-fluorophenyl)propanoic acid 
• 18125-46-7 (R)-4-fluorophenylalanine 

Downstream Products

• 328273-02-5 (2R,5S)-methyl 5-(benzyloxycarbonylamino)-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoate 
• 328273-06-9 C₁₆H₂₂FNO₃ 
• 223526-67-8 (2R,5S)-5-(tert-butoxycarbonylamino)-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanic acid 
• 799270-24-9 (S,E)-ethyl 4-((2R,5S)-5-(tert-butoxycarbonylamino)-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanamido)-5-((S)-2-oxopyrrolidin-3-yl)pent-2-enoate 

Relevant articles and documents

Improved synthesis of rupintrivir

An improved synthesis of rupintrivir (AG7088) was accomplished using three amino acids (l-glutamic acid, d-4-fluorophenylalanine, and l-valine) as the building blocks. The key fragment ketomethylene dipeptide isostere was constructed with the valine derivative and phenylpropionic acid derivative, followed by coupling with a lactam derivative and an isoxazole acid chloride to provide AG7088 totally in eight steps.