1427669-81-5Relevant articles and documents
Palladium-catalyzed C2-acylation of indoles with aryl and alkyl aldehydes
Yan, Xiao-Biao,Shen, Yong-Wen,Chen, Dao-Qian,Gao, Pin,Li, Ying-Xiu,Song, Xian-Rong,Liu, Xue-Yuan,Liang, Yong-Min
, p. 7490 - 7495 (2014)
A palladium-catalyzed C2-acylation of indoles with aryl and alkyl aldehydes via C-H functionalization is reported. The method shows excellent functional group tolerance and provides a straightforward way for the preparation of 2-aroylindoles.
Direct C-2 acylation of indoles with toluene derivatives via Pd(II)-catalyzed C-H activation
Zhao, Yaping,Sharma, Upendra K.,Schr?der, Felix,Sharma, Nandini,Song, Gonghua,Van Der Eycken, Erik V.
, p. 32559 - 32563 (2017/07/07)
A simple and efficient Pd-catalyzed method for the C2-acylation of indoles is described. Less toxic, stable, and commercially available toluene derivatives were used as acyl sources, with tert-butylhydroperoxide (TBHP) as oxidant and pivalic acid as addit
Palladium-catalyzed C2-acylation of indoles with α-diketones assisted by the removable N-(2-pyrimidyl) group
Li, Chunpu,Zhu, Wei,Shu, Shuangjie,Wu, Xiaoming,Liu, Hong
, p. 3743 - 3750 (2015/06/16)
An effective and practical palladium-catalyzed C2-acylation method was successfully developed for the synthesis of 2-acylindoles. A variety of 2-acylindoles were readily prepared from N-pyrimidyl indoles in moderate to good yields. This methodology offers
