89902-44-3Relevant articles and documents
Enantiopure sulfoximines-catalyzed 1, 4-additions to 2-en-ketone
Zhao, Hongwei,Han, Hui,Yang, Hengquan,wang, Li
, p. 210 - 213 (2018/06/26)
An efficient chiral catalyst procedure for the preparation of β-chiral ketone via the 1, 4-additions reaction of 2-en-ketone has been developed using enantiopure sulfoximines modified with functional groups as ligands. The carefully design and synthesized
An Iodine-Mediated Hofmann-L?ffler-Freytag Reaction of Sulfoximines Leading to Dihydroisothiazole Oxides
Zhang, Duo,Wang, Han,Cheng, Hanchao,Hernández, José G.,Bolm, Carsten
supporting information, p. 4274 - 4277 (2017/10/23)
A Hofmann-L?ffler-Freytag type cyclization reaction of S-aryl-S-phenylpropyl sulfoximines (and related derivatives) was developed. Using molecular iodine as the initiator under visible light a series of five-membered cyclic products was obtained in moderate to high yields. The approach represents a new strategy for the synthesis of dihydroisothiazole oxides and benzo[d]isothiazoles-1-oxides. (Figure presented.).
Sulfoximines: A reusable directing group for chemo-and regioselective ortho C-H oxidation of arenes
Yadav, M. Ramu,Rit, Raja K.,Sahoo, Akhila K.
supporting information; experimental part, p. 5541 - 5545 (2012/06/01)
Sulfoximines direct: A new protocol for the chemo-and regioselective ortho C-H acetoxylation of arenes in N-benzoylated sulfoximines is reported. The sulfoximine directing group is easily detached from the C-H oxidation product through acid-promoted hydrolysis, isolated, and reused (see scheme). The meta-substituted phenols are synthesized following this strategy and the stereointegrity of the sulfoximine is preserved in this transformation. C(sp3)-H acetoxylation of the methyl group is also demonstrated.
An unexpected cyclization reaction of tert-butyl o-trimethylsilylphenyl sulfoximine
Schmidt, Joerg Christoph,Adiwidjaja, Gunadi,Schaumann, Ernst
, p. 104 - 109 (2013/09/24)
An efficient one-pot synthesis of the title compound 5 starting from methyl phenyl sulfoximine is described. On attempted iododesilylation of this compound using iodine chloride, one methyl group on the silicon atom is formally replaced by the imino nitrogen to give a derivative 8 of the novel heterocyclic system 1,3,2-benzothiasilazole. ARKAT-USA, Inc.
Ortho-Lithiation of S-tert-butyl-S-phenylsulfoximines. New route to enantiopure sulfinamides via a de-tert-butylation reaction
Gaillard, Stéphane,Papamica?l, Cyril,Dupas, Georges,Marsais, Francis,Levacher, Vincent
, p. 8138 - 8147 (2007/10/03)
The sulfoximine group proved to be an excellent ortho-directing group in lithiation reactions. Several electrophiles were used to afford the corresponding ortho-functionalized aryl sulfoximines in good yields. The use of prochiral electrophiles lead to mo
Structure of Silylated Sulfonamides; a Silicon-29 Nuclear Magnetic Resonance Investigation
Iley, Jim,Bassindale, Alan R.,Patel, Pravin
, p. 77 - 80 (2007/10/02)
The structures of eighteen silylsulfonamides have been determined by 29Si n.m.r.The chemical shifts of the compounds were compared with those of model compounds.The N-silyl tautomer was the only isomer observed, except in cases where strongly electron-withdrawing groups (e.g.Cl, NMe2) were attached to nitrogen; in such cases the O-silyl tautomer dominates.The results have been rationalised in terms of the effect of substituents on the S-N ?-bond order.An estimate of the hitherto unmeasured S=N molar bond enthalpy as 325 kJ mol-1 was obtained.
