1428188-87-7Relevant articles and documents
Guidelines for β-lactam synthesis: Glycal protecting groups dictate stereoelectronics and [2+2] cycloaddition kinetics
Grinstaff, Mark W.,Balijepalli, Anant S.,McNeely, James H.,Hamoud, Aladin
, p. 12044 - 12057 (2020)
The alkene-isocyanate cycloaddition method affords β- lactams from glycals with high regio- and stereoselectivity, but the factors that determine substrate reactivity are poorly understood. Thus, we synthesized a library of 17 electron-rich alkenes (glyca