142860-83-1

Basic information

• Product Name: Benzene, 1-[(3-butenyloxy)methyl]-4-methoxy-
• CAS NO: 142860-83-1
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 142860-83-1.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(3-butenyloxy)methyl]-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(3-butenyloxy)methyl]-4-methoxy-(142860-83-1)
• EPA Substance Registry System: Benzene, 1-[(3-butenyloxy)methyl]-4-methoxy-(142860-83-1)

Safety Data

• Hazardous Substances Data: 142860-83-1(Hazardous Substances Data)

Upstream product

• 627-27-0 homoalylic alcohol 
• 824-94-2 p-methoxybenzyl chloride 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 142860-84-2 4-(p-methoxybenzyloxy)-1,2-epoxybutane 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 142860-84-2 4-(p-methoxybenzyloxy)-1,2-epoxybutane 
• 167629-46-1 (p-methoxybenzyloxy)-2-hydroxybutanol 
• 869348-65-2 (S)-1-(4-Methoxy-benzyloxy)-hept-6-en-3-ol 
• 870680-53-8 Methanesulfonic acid (S)-1-[2-(4-methoxy-benzyloxy)-ethyl]-pent-4-enyl ester 
• 870680-55-0 (E)-(S)-6-Hydroxy-8-(4-methoxy-benzyloxy)-oct-2-enoic acid ethyl ester 
• 870680-59-4 (R)-{(2S,5R)-5-[2-(4-Methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-methoxymethoxy-acetaldehyde 
• 870680-58-3 (S)-2-{(2S,5R)-5-[2-(4-Methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-2-methoxymethoxy-ethanol 
• 870680-56-1 (R)-Hydroxy-{(2S,5R)-5-[2-(4-methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-acetic acid ethyl ester 
• 869348-17-4 (+)-(S,E)-ethyl 8-((4-methoxybenzyl)oxy)-6-((methylsulfonyl)oxy)oct-2-enoate 
• 870680-57-2 (R)-{(2S,5R)-5-[2-(4-Methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-methoxymethoxy-acetic acid ethyl ester 
• 870680-72-1 (1S,2R,3R)-1-{(2S,5R)-5-[2-(4-Methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-1-methoxymethoxy-3-methyl-5-trimethylsilanyl-pent-4-yn-2-ol 
• 870680-61-8 2,2-Dimethyl-propionic acid (1R,2R)-1-((R)-{(2S,5R)-5-[2-(4-methoxy-benzyloxy)-ethyl]-tetrahydro-furan-2-yl}-methoxymethoxy-methyl)-2-methyl-4-trimethylsilanyl-but-3-ynyl ester 
• 193416-58-9 (2S)-4-[(4-methoxybenzyl)oxy]butane-1,2-diol 
• 195257-62-6 (R)-2-(2-((4-methoxybenzyl)oxy)ethyl)oxirane 

Relevant articles and documents

The first stereoselective synthesis of dendrodolide A

The first stereoselective total synthesis of natural product, dendrodolide A (1) is described from readily available (R)-propylene oxide and 3-buten-1-ol as starting materials. The synthesis was achieved in 10 steps with an overall yield of 19.1%. The key steps involved in the synthesis are Jacobsen hydrolytic kinetic resolution, epoxide ring opening with 2-allyl-1, 3-dithiane, Yamaguchi esterification, and ring-closing metathesis (RCM).

Total synthesis, biological evaluation of dendrodolides A–D and their analogues

A concise total synthesis of dendrodolides A–D (1–4) has been accomplished in 10 steps from commercially available (R)-propylene oxide and 3-buten-1-ol as starting materials. The key steps involved in the synthesis are Jacobsen hydrolytic kinetic resolution, epoxide ring opening with 2-allyl-1, 3-dithiane, Yamaguchi esterification and ring-closing metathesis (RCM). In addition, a series of ester derivatives were prepared utilizing Yamaguchi esterification at the C-3 position of the dendrodolide core and screened for their efficacy against cancer cell lines.

Diastereoselective and Branched-Aldehyde-Selective Tandem Hydroformylation-Hemiaminal Formation: Synthesis of Functionalized Piperidines and Amino Alcohols

Starting from readily available allylglycine, a tandem hydroformylation-hemiaminal formation reaction has been developed for the synthesis of chiral functionalized piperidines, with very good diastereoselectivity and branched regioselectivity using Rh/(S,

ANTIVIRAL COMPOUNDS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus v