167629-46-1

Upstream product

• 142860-83-1 1-(4-methoxybenzyloxy)-3-butene 
• 2746-25-0 p-Methoxybenzyl bromide 
• 824-94-2 p-methoxybenzyl chloride 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 167629-45-0 4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane 

Downstream Products

• 289486-00-6 1-(4,4'-dimethoxytrityloxy)-4-(p-methoxybenzyloxy)butan-2-ol 
• 208719-54-4 [2-[1-Benzenesulfonyl-1-fluoro-meth-(E)-ylidene]-4-(4-methoxy-benzyloxy)-butoxy]-tert-butyl-dimethyl-silane 
• 208719-57-7 Benzoic acid 2-[1-fluoro-meth-(Z)-ylidene]-4-(4-methoxy-benzyloxy)-butyl ester 
• 167629-48-3 1-[(tert-butyldimethylsilyl)oxy]-4-[(4-methoxybenzyl)oxy]butan-2-one 
• 289486-03-9 1-(4,4'-dimethoxytrityloxy)-4-(p-methoxybenzyloxy)-2-methylenebutane 
• 289486-02-8 1-(4,4'-dimethoxytrityloxy)-4-(p-methoxybenzyloxy)butan-2-one 
• 1026475-63-7 1-{2-[2-(4-methoxy-benzyloxy)-ethyl]-allyl}-5-methyl-1H-pyrimidine-2,4-dione 
• 167629-40-5 4-[(4-methoxybenzyl)oxy]-2-methylenebutan-1-ol 
• 1026888-84-5 2-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-4-(4-methoxy-benzyloxy)-butyronitrile 
• 639008-44-9 (E)-2-(tert-butyldiphenylsilyloxymethyl)-4-(4-methoxy-benzyloxy)-2-butenenitrile 
• 639008-43-8 1-(tert-butyldiphenylsilyloxy)-4-(4-methoxy-benzyloxy)-butan-2-one 
• 167629-45-0 4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane 
• 639008-42-7 1-(tert-butyldiphenylsilyloxy)-4-(4-methoxy-benzyloxy)-butan-2-ol 
• 167629-47-2 1-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-butan-2-ol 

Relevant academic research and scientific papers

Isolation and synthesis of a novel β-carboline guanidine derivative tiruchanduramine from the Indian ascidian Synoicum macroglossum

The isolation and synthesis of the racemic form of a novel β-carboline guanidine alkaloid, tiruchanduramine, a potent α-glucosidase inhibitor from the Indian ascidian, Synoicum macroglossum has been achieved.

A facile and convergent synthesis of sarmentosin

A concise synthesis of sarmentosin (1) starting from butane-1,2,4-triol-1,2-acetonide is described. This convergent route can also be employed for the preparation of sarmentosin analogues for structure-activity relationship studies.

Synthesis of aglycon analogues of sarmentosin and their bioactivity of lymphocyte proliferation.

A number of aglycon analogues of sarmentosin were prepared and their bioactivities on the proliferation of T-lymphocytes and B-lymphocytes were assayed.

An efficient and selective method for hydrolysis of acetonides

Acetonide was selectively and efficiently cleaved with cerium (III) chloride heptahydrate and oxalic acid in acetonitrile. This method was found to be of good functionalities compatibility with such acid sensitive groups as Tr, PMB, TBDMS, TBDPS, OAc, OBz, OTs, OTf.

Synthesis of unsaturated carboacyclic nucleoside analogues via Mitsunobu reactions

2-Substituted allyl alcohols 9 and 14 were prepared starting from butane-1,2,4-triol and glycerol, respectively. Mitsunobu condensations of 9 and 14 with purine and pyrimidine bases, followed by deprotection, afforded a number of acyclonucleosides having

Terminal fluoroolefins. The synthesis of novel carboacyclic nucleosides

A facile preparation of ketone 7 from butanetriol acetonide 5 is reported, and its utility for the synthesis of novel carboacyclic nucleosides 3E, 3Z, 4E and 4Z by the selective manipulation of multiple functionalities is demonstrated.