142874-62-2

Basic information

• Product Name: Benzofuran, 2,3-dihydro-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-
• CAS NO: 142874-62-2
• Molecular Formula: C20H24O
• Molecular Weight: 280.41
• Mol File: 142874-62-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzofuran, 2,3-dihydro-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 2,3-dihydro-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-(142874-62-2)
• EPA Substance Registry System: Benzofuran, 2,3-dihydro-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-(142874-62-2)

Safety Data

• Hazardous Substances Data: 142874-62-2(Hazardous Substances Data)

Upstream product

• 13716-12-6 tri-tert-butyl phosphine 
• 106-38-7 para-bromotoluene 
• 697-82-5 2,3,5-trimethylphenol 
• 78-84-2 isobutyraldehyde 
• 67-64-1 acetone 
• 50390-51-7 4'-methylisobutyrophenone 
• 14289-68-0 2-bromo-2-methyl-1-(4-methylphenyl)-1-propanone 
• 488834-29-3 2-methyl-1-(4-methylphenyl)-2-(2,3,5-trimethylphenoxy)propan-1-ol 
• 142874-49-5 1-(2-Methoxy-3,4,6-trimethylphenyl)-1-(4-methylphenyl)-2-methylpropanol 
• 103323-59-7 2-methoxy-3,4,6-trimethylbromobenzene 
• 32454-12-9 2-methyl-2-(4-methylphenyl)propionaldehyde 

Downstream Products

• 877776-23-3 1-(4-nitrophenyl)-2-[2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]diazene 
• 274907-44-7 (+)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine 
• 488834-30-6 5-bromo-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran 
• 142874-71-3 2,2,4,6,7-Pentamethyl-3-(4-methylphenyl)-5-nitro-2,3-dihydrobenzofuran 

Relevant articles and documents

AZO COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF

A process for the production of an aromatic azo compound having a 2,3-dihydrobenzofuran ring bearing a diazo group at the 5-position of the ring by conducting the diazo coupling of a 2,3-dihydrobenzofuran derivative represented by the general formula (II): [wherein R1 and R2 are each independently C1-6 alkyl; R3 is optionally substituted aryl; and R4, R5 and R6 are each independently hydrogen, C1-6 alkyl, halogeno, C1-6 alkoxy, or C1-6 alkylthio] with a benzenediazonium salt having an electron-withdrawing group at the p- and/or o-position in a mixed solvent composed of water and a polar organic solvent.

A convenient ring formation of 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans from phenols and 2-aryl-2,2-dialkylacetaldehydes

A new and simple route for the preparation of 3-aryl-2,2-dialkyl-2,3- dihydrobenzofurans from phenols is described. In the presence of an acid catalyst phenols react with 2-aryl-2,2-dialkylacetaldehydes, prepared in good yield from 2-arylacetonitriles in 2 steps, to give 3-aryl-2,2-dialkyl-2,3- dihydrobenzofurans. Electron-donating substituents were required on the phenols in order to give 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans in good yield.

5-Aminocoumarans: Dual inhibitors of lipid peroxidation and dopamine release with protective effects against central nervous system trauma and ischemia

A series of 2,3-dihydro-5-benzofuranamines (5-aminocoumarans) were developed for the treatment of traumatic and ischemic central nervous system (CNS) injury. Compounds within this class were extremely effective inhibitors of lipid peroxidation in vitro an