1429172-06-4Relevant academic research and scientific papers
Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents
Dheer, Divya,Behera, Chittaranjan,Singh, Davinder,Abdullaha, Mohd,Chashoo, Gousia,Bharate, Sandip B.,Gupta, Prem N.,Shankar, Ravi
, (2020/09/17)
Herein, a series of triaryl-1,2,3-triazoles, in order to check cytotoxicity on breast cancer cell lines have been synthesized with pendent benzyl ring to mimic the phenolic A ring of Tamoxifene. The biological results indicated that most of the compounds
Copper-Catalyzed Decarboxylative Cycloaddition of Propiolic Acids, Azides, and Arylboronic Acids: Construction of Fully Substituted 1,2,3-Triazoles
Li, Ya-Min,Li, Yi,Wang, Xiang-Xiang,Xia, Wen-Jin,Xin, Yangchun,Ye, Rui-Rong,Zhou, Bin
, p. 3576 - 3586 (2020/03/23)
A copper-catalyzed decarboxylative cycloaddition of propiolic acids, azides, and arylboronic acids is described. The present reaction provides an efficient and convenient method for the synthesis of various fully substituted 1,2,3-Triazoles from readily available starting materials. A possible mechanism is proposed.
Pd-catalyzed ligand-free C(5)–H arylation of 1,4-disubstituted 1,2,3-triazoles promoted by microwaves
Zhao, Fen,Tian, Wen-Hai,Luo, Fang,Cheng, Hui-Ling,Jiang, Yu-Bo,Chen, Zhen
supporting information, p. 1678 - 1686 (2016/10/21)
Pd(OAc)2-catalyzed regioselective C(5)–H arylation of 1,4-disubstituted 1,2,3-triazoles was achieved without ligand under microwave conditions in 1 h, generating 1,4,5-trisubstituted 1,2,3-triazoles with good to excellent yields. The obtained molecules can be easily converted into 4,5-disubstituted 1,2,3-triazoles through the debenzylation process with one-pot manipulation.
Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide: One-pot strategy toward trisubstituted triazoles
Wei, Fang,Li, Haoyu,Song, Chuanling,Ma, Yudao,Zhou, Ling,Tung, Chen-Ho,Xu, Zhenghu
supporting information, p. 2860 - 2863 (2015/06/16)
A Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide has been developed. By using this Cu/Pd transmetalation relay catalysis, a variety of 1,4,5-trisubstituted 1,2,3-triazoles were quickly assembled in one step in high yield
[Cu8(μ8-H){S2P (OEt)2} 6](PF6): A novel catalytic hydride-centered copper cluster for azide-alkyne cycloaddtion
Lee, Bo-Han,Wu, Cheng-Chieh,Fang, Xuan,Liu,Zhu, Jia-Liang
, p. 572 - 577 (2013/07/11)
A hydride-centered dithiophosphate cluster [Cu8(μ 4-H){S2P(OEt)2}6](PF6) (1)] previously developed by us was applied as a new catalyst to the 1,3-dipolar cycloaddition of organic azides and
