1429896-46-7

Basic information

• Product Name: 1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclopentanecarboxamide
• Synonyms: 1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclopentanecarboxamide
• CAS NO: 1429896-46-7
• Molecular Weight: 360.456
• Mol File: 1429896-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclopentanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclopentanecarboxamide(1429896-46-7)
• EPA Substance Registry System: 1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclopentanecarboxamide(1429896-46-7)

Safety Data

• Hazardous Substances Data: 1429896-46-7(Hazardous Substances Data)

Upstream product

• 1429896-60-5 1-methyl-N-(quinolin-8-yl)cyclopentane-1-carboxamide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 5453-85-0 ethyl cyclopentanecarboxylate 
• 20023-50-1 1-methylcyclopentanecarbonyl chloride 
• 5217-05-0 1-methylcyclopentanecarboxylic acid 
• 6553-72-6 ethyl 1-methyl-1-cyclopentanecarboxylate 

Relevant articles and documents

β-Arylation of carboxamides via iron-catalyzed C(sp3)-H bond activation

A 2,2-disubstituted propionamide bearing an 8-aminoquinolinyl group as the amide moiety can be arylated at the β-methyl position with an organozinc reagent in the presence of an organic oxidant, a catalytic amount of an iron salt, and a biphosphine ligand at 50 C. Various features of selectivity and reactivity suggest the formation of an organometallic intermediate via rate-determining C-H bond cleavage rather than a free-radical-type reaction pathway.