14304-27-9

Basic information

• Product Name: 1-PENTEN-4-YN-3-OL
• Synonyms: 1-PENTEN-4-YN-3-OL;1-PENTEN-4-YN-3-OL,97%
• CAS NO: 14304-27-9
• Molecular Formula: C₅H₆O
• Molecular Weight: 82.1
• Mol File: 14304-27-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 111.376 °C at 760 mmHg
• Flash Point: 6.887 °C
• Appearance: /
• Density: 0.935 g/cm³
• Vapor Pressure: 11.85mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: 1-PENTEN-4-YN-3-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PENTEN-4-YN-3-OL(14304-27-9)
• EPA Substance Registry System: 1-PENTEN-4-YN-3-OL(14304-27-9)

Safety Data

• Hazardous Substances Data: 14304-27-9(Hazardous Substances Data)

Usage

Physical state

Colorless liquid 1-Penten-4-yn-3-ol is a liquid that appears colorless, meaning it does not have any visible color to the naked eye.

Odor

Fruity or floral The compound has a distinct smell that can be described as a combination of fruity and floral notes.

Solubility

Insoluble in water, soluble in organic solvents 1-Penten-4-yn-3-ol does not dissolve well in water but can dissolve in many organic solvents, such as ethanol or acetone.

Uses

Different sources of media describe the Uses of 14304-27-9 differently. You can refer to the following data:
1. Intermediate in synthesis of pharmaceuticals and agrochemicals The compound is primarily used as an intermediate in the production of various pharmaceuticals and agrochemicals, which are chemicals used in agriculture to protect crops from pests and diseases.
2. Reagent in organic synthesis 1-Penten-4-yn-3-ol is also used as a reagent, or a reactant, in organic synthesis, which is the process of creating new organic compounds through chemical reactions.
3. Building block in production of fragrances and flavors The compound serves as a building block, or a starting material, in the production of various fragrances and flavors used in the perfumery and flavoring industries.

Potential properties

Antioxidant, antibacterial, and anti-inflammatory 1-Penten-4-yn-3-ol has been studied for its potential properties, which include antioxidant (preventing or slowing down oxidation), antibacterial (resisting or killing bacteria), and anti-inflammatory (reducing inflammation) effects.

Industrial and research applications

Versatile compound Due to its various potential properties and uses, 1-Penten-4-yn-3-ol is considered a versatile compound with applications in different industries and research fields.

Safety precautions

Flammability and hazardous effects 1-Penten-4-yn-3-ol should be handled and stored with care due to its flammability (ability to catch fire) and possible hazardous effects on health or the environment.

InChI:InChI=1/C5H6O/c1-3-5(6)4-2/h1,4-6H,2H2

Upstream product

• 4301-15-9 ethynyldimagnesium dibromide 
• 107-02-8 acrolein 
• 4301-14-8 acetylenemagnesium bromide 
• 1066-26-8 sodium acetylide 
• 74-86-2 acetylene 
• 18295-60-8 allenylmagnesium bromide 
• 70277-75-7 lithium acetylide 
• 7664-41-7 ammonia 
• 124399-64-0 3-hydroxy-4-penten-1-ynyltrimethylsilane 

Downstream Products

• 600-14-6 2,3-Pentanedione 
• 922-65-6 divinylcarbinol 
• 82586-09-2 5-phenylsulfinyl-3-penten-1-yne 
• 40964-63-4 1-phenyl-4-penten-1-yn-3-ol 
• 1027295-88-0 4-(2-methyl-benzyl)-5-vinyl-furan-3-carboxylic acid ethyl ester 
• 1026772-06-4 [OsCl₂(P(C₆H₅)3)2(CHC(P(C₆H₅)3)CH(OH)CHCH₂)] 
• 1426257-69-3 C₁₄H₁₅NO₂ 
• 4949-20-6 2,4-pentadien-1-ol 
• 852046-83-4 3-(2-methyl-benzyl)-furan-2,4-dicarboxylic acid 4-ethyl ester 
• 852046-91-4 5-formyl-4-(2-methyl-benzyl)-furan-3-carboxylic acid ethyl ester 
• 698-14-6 3--propin-(1)-on-(3) 
• 584-02-1 2-pentanol 
• 19833-08-0 pentadeca-1,8t,10t-triene-4,6-diyn-3-ol 
• 65892-84-4 heptadeca-1,9c-diene-4,6-diyne-3,8-dione 

Relevant articles and documents

Synthesis of isoxazole derivatives of 4,5-dihydro-1H-pyrazole

Cyclocondensation of pent-1-en-4-yn-3-one with phenylhydrazine and p-tolylhydrazine occurs at the positions 1, 3. Proceeding from the 1-aryl-3-ethynyl-4,5-dihydro-1H-pyrazoles formed in the reaction in yields up to 95% we prepared potentially biologically

Quantitative studies and sensory analyses on the influence of cultivar, spatial tissue distribution, and industrial processing on the bitter off-taste of carrots (Daucus carota L.) and carrot products

Although various reports pointed to 6-methoxymellein (1) as a key player imparting the bitter taste in carrots, activity-guided fractionation experiments recently gave evidence that not this isocoumarin but bisacetylenic oxylipins contribute mainly to the off-taste. Among these, (Z)-heptadeca-1,9-dien-4,6- diyn-3-ol (2), (Z)-3-acetoxy-heptadeca-1,9-dien-4,6-diyn-8-ol (3), and (Z)-heptadeca-1,9-dien-4,6-diyn-3,8-diol (falcarindiol, 4) have been successfully identified. In the present study, an analytical procedure was developed enabling an accurate quantitation of 1-4 in carrots and carrot products. To achieve this, (E)-heptadeca-1,9-dien-4,6-diyn-3,8-diol was synthesized as a suitable internal standard for the quantitative analysis of the bisacetylenes. On the basis of taste activity values, calculated as the ratio of the concentration and the human sensory threshold of a compound, a close relationship between the concentration of 4 and the intensity of the bitter off-taste in carrots, carrot puree, and carrot juice was demonstrated, thus showing that compound 4 might offer a new analytical measure for an objective evaluation of the quality of carrot products. Quantitative analysis on the intermediate products in industrial carrot processing revealed that removing the peel as well as green parts successfully decreased the concentrations in the final carrot puree by more than 50%.

Synthesis and cytotoxic activity of a series of diacetylenic compounds related to falcarindiol

The synthesis of a series of diacetylenic compounds related to the natural product falcarindiol has been carried out. Unsymmetrical diacetylenes were prepared by a modification of the Cadiot-Chodkiewicz coupling reaction, while a Glaser coupling was used to prepare symmetrical diacetylenes. These compounds have been tested for in vitro cytotoxic activity against Hep-G2, and H-4-II-E cell lines. Diacetylenes with additional unsaturation at C-1, 2, appended with hydroxyl groups at C-3 and C-8, or with long hydrophobic chains, exhibited IC50 values in the micromolar range.