1430475-55-0Relevant academic research and scientific papers
Determination of absolute configuration of secondary alcohols using thin-layer chromatography
Wagner, Alexander J.,Rychnovsky, Scott D.
, p. 4594 - 4598 (2013)
A new implementation of the competing enantioselective conversion (CEC) method was developed to qualitatively determine the absolute configuration of enantioenriched secondary alcohols using thin-layer chromatography. The entire process for the method requires approximately 60 min and utilizes micromole quantities of the secondary alcohol being tested. A number of synthetically relevant secondary alcohols are presented. Additionally, 1H NMR spectroscopy was conducted on all samples to provide evidence of reaction conversion that supports the qualitative method presented herein.
