14309-24-1

Upstream product

• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 283156-23-0 3-isopropenyl-3-methyl-cyclobut-1-ene-1,2-dicarboxylic acid dimethyl ester 
• 1829-60-3 dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate 

Downstream Products

• 17649-59-1 dimethyl 4,5-dimethylphthalate 
• 91061-82-4 4,5-dimethylcyclohexa-1,4-diene-1,2-dicarboxylic acid 
• 92775-06-9 1,2-bis(hydroxymethyl)-4,5-dimethylcyclohexa-1,4-diene 
• 33383-76-5 4,5-Dimethyl-cyclohexane-1,2-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Diels-Alder reactions: The effects of catalyst on the addition reaction

Abstract The reaction between 2,3-dimethyl-1,3-butadiene and dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate is efficiently achieved with small amounts of catalyst, i.e. phenol, AcOH, nafion, and β-cyclodextrin. Exo-diastereoselective cycloa

Flapping viscosity probe that shows polarity-independent ratiometric fluorescence

A variety of fluorescent molecular viscosity probes have been widely used for mapping the local viscosity in cells and for monitoring the microenvironments in materials. However, their viscosity-sensing structural design still relies strongly on molecular

Fluorous imidazolium room-temperature ionic liquids based on HFPO trimer

Imidazole substituted with a polyfluoropolyether chain based on HFPO trimer combined with various polyfluoroalkyl triflates produced novel highly fluorous ionic liquids. Their metathesis with four different anions generated a final set of 20 fluorous ionic liquids of waxy or viscous liquid character, which are all soluble in perfluorinated solvents. Two model reactions using selected ionic liquid, the opening of a THF ring with benzoyl chloride under Friedel-Crafts conditions and substitution of benzyl chloride with sodium azide, led to decomposition of the ionic liquid. However, Diels-Alder reaction of 2,3-dimethylbuta-1,3-diene with dimethyl acetylenedicarboxylate in a fluorous ionic liquid resulted in a reasonable enhancing of the reaction rate with smooth recycle of the fluorous solvent. The fluorophilicity of these fluorous ionic liquids ranges from more than 10 for water, toluene or dichloromethane to less than 0.2 for acetonitrile or methanol.

The ring expansion of a dimethyl-substituted vinylcyclobutene derivative by metal complexes that can undergo an inner-sphere electron transfer

The ring expansion of a dimethyl-substituted vinylcyclobutene derivative to the corresponding dimethyl-substituted cyclohexadiene or aromatic compound was studied. It was found that metal complexes of Ni(I), Ti(III), Sm(II), and Fe(II), which can undergo

Highly-functionalized arene synthesis based on palladium on carbon-catalyzed aqueous dehydrogenation of cyclohexadienes and cyclohexenes

Transition metal-catalyzed dehydrogenation is a clean oxidation method requiring no additional oxidants. We have accomplished a heterogeneous Pd/C-catalyzed aqueous dehydrogenation of 1,4-cyclohexadienes and cyclohexenes to give the corresponding highly-functionalized arenes. Furthermore, various arenes could be efficiently constructed in a one-pot manner via a Diels-Alder reaction and the following dehydrogenation.

Fullerene Derivatives and Organic Electronic Device Comprising the Same

The present invention relates to fullerene derivatives and an organic electronic device using the same, and more specifically, to a novel fullerene derivative incorporating an aromatic fused ring compound and to an organic electronic device with excellent

FULLERENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME

The present invention relates to fullerene derivatives and an organic electronic device using the same, and more specifically, to a novel fullerene derivative incorporating an aromatic fused ring compound and to an organic electronic device with excellent

2,3-DIHYDRO-1H-ISOINDOL-1-IMINE DERIVATIVES USEFUL AS THROMBIN PAR-1 RECEPTOR ANTAGONIST

The present invention is directed to novel 2,3-dihydro-1H-isoindol-1-imine derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the thrombin PAR-1 receptor antagonists.

Design and synthesis of benzosultine-sulfone as a o -Xylylene precursor via cross-enyne metathesis and rongalite: Further expansion to polycyclics via regioselective diels-alder reaction

Benzosultine-sulfone 5 has been prepared as a o-xylylene or o-quinodimethane precursor by utilization of rongalite. Thermal activation of this hybrid molecule 5 has resulted a new sulfone-based building block 6. Building block 5 is a suitable precursor for the synthesis of unsymmetrically functionalized polycyclics through Diels-Alder (DA) chemistry. The dibromosulfone 24 and benzosultine-sulfone 5 has also been used for the synthesis of various sulfone based unnatural α-amino acid (AAA) derivatives.

Synthesis, Fungicidal Activity, and Effects on Fungal Polyamine Metabolism of Novel Cyclic Diamines

A number of novel, cyclic diamines were synthesized and examined for fungicidal activity as part of a continuing program of work on polyamine analogues. The novel synthetic cyclic diamines trans-1,2-bis(diethylaminomethyl)cyclopentane (compound 1) and trans-5,6-bis(aminomethyl)bicyclo[2.2.1]-hept-2-ene (compound 2) and the synthetic cyclic diamine 1,2-bis(dimethylaminomethyl)-4,5-dimethylcyclohexa-1,4-diene (compound 3) controlled the important crop pathogen Erysiphe graminis DC f.sp. hordei Marchai. Since E. graminis cannot be cultured in vitro, the effects of the three diamines on polyamine biosynthesis were studied using the fungal pathogen Pyrenophora avenae Ito & Kuribay. All three compounds were effective in reducing the growth of P. avenae in vitro and in altering polyamine levels. However, whereas compound 1 reduced concentrations of all three polyamines, compound 2 increased spermidine 2-fold and compound 3 had little effect on spermidine and spermine concentrations but reduced putrescine concentration by 69%. These changes in polyamine concentrations could not be correlated with changes in activities of biosynthetic enzymes. It seems therefore that although these novel cyclic diamines alter fungal polyamine metabolism, their effects on the growth of P. avenae may not be related to depletion of cellular polyamines.