1431545-40-2Relevant academic research and scientific papers
Catalyst-free Mannich reaction of hydroxyanthraquinone: Facile access to emodin Mannich bases and anthraoxazines
Zhao, Li-Ming,Zhang, Li-Ming,Ma, Feng-Yan,Wang, Xiang-Shan,Jin, Hai-Shan
, p. 2802 - 2805 (2013/06/05)
A simple and efficient method for derivatization of hydroxyanthraquinone natural product emodin through catalyst-free Mannich reaction is described. The method allows the modification of emodin skeleton at 2-position. This new derivatization strategy to emodin provides a clear advantage over traditional approaches, due to its easy operation and efficiency that does not involve the protection and deprotection.
