143191-76-8

Upstream product

• 532-20-7 D-xylofuranose 
• 4105-29-7 [(3aR,5S,6aR)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzoate 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 160999-15-5 5-O-benzoyl-3-O-(1-imidazolylthiocarbonyl)-1,2-O-isopropylidene-α-D-xylofuranose 
• 98-88-4 benzoyl chloride 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 98-59-9 p-toluenesulfonyl chloride 
• 143191-75-7 2(S)-(O-benzoylmethyl)tetrahydrofuran-4(R)-ol 
• 143191-74-6 methyl 5-O-benzoyl-3-deoxy-D-erythro-pentofuranose 

Downstream Products

• 143191-79-1 4(S)-<3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl>tetrahydro-2(S)-furanmethanol benzoate 
• 143191-79-1 2(S)-(O-benzoylmethyl)-4(S)-<3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl>tetrahydrofuran 
• 151223-91-5 4(S)-<3,4-dihydro-2,4-dioxo-5-methyl-1(2H)-pyrimidinyl>tetrahydro-2(S)-furanmethanol benzoate 
• 151223-91-5 2(S)-(O-benzoylmethyl)-4(S)-<3,4-dihydro-2,4-dioxo-5-methyl-1(2H)-pyrimidinyl>tetrahydrofuran 
• 151223-88-0 2(S)-(O-benzoylmethyl)-4(S)-(6-chloro-9H-purin-9-yl)tetrahydrofuran 
• 160999-07-5 4(S)-(2-amino-6-chloro-9H-purin-9-yl)-2(S)-(O-benzoylmethyl)tetrahydrofuran 
• 143191-83-7 1-[(3S,5S)-5-(hydroxymethyl)tetrahydrofuran-3-yl]thymine 
• 160999-09-7 2(S)-(O-benzoylmethyl)-4(S)-(6-cyclopropylamino-9H-purin-9-yl)tetrahydrofuran 
• 160999-14-4 4(S)-<3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl>-2(S)-(p-O-toluenesulfonylmethyl)tetrahydrofuran 
• 160999-12-2 N-<<<(2S,4S)-2-(O-benzoylmethyl)tetrahydrofuranyl>amino>carbonyl>-3-ethoxy-2-propenamide 
• 143191-78-0 Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester 
• 143191-80-4 2(S)-(O-benzoylmethyl)-4(S)-<4-(1,2,4-triazolyl)-2-oxo-1(2H)-pyrimidinyl>tetrahydrofuran 
• 151223-92-6 4(S)-<4-amino-2-oxo-1(2H)-pyrimidinyl>-2(S)-(O-benzoylmethyl)tetrahydrofuran 
• 175470-63-0 Benzoic acid (2S,4S)-4-(2-amino-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester 

Relevant academic research and scientific papers

Novel isomeric dideoxynucleosides as potential antiviral agents

Novel isomeric dideoxynucleosides with S,S absolute stereochemistry and involving the transposition of the base moiety from the normal 1'- to the 2'-position have been regiospecifically and stereospecifically synthesized. The synthetic approaches involved

THE SYNTHESIS OF (S) AND (R) ENANTIOMERS OF NOVEL HYDROXYMETHYLATED ISODIDEOXYNUCLEOSIDES

Novel isomeric dideoxynucleosides, with symmetry introduced at the 2'-position (4'-position using normal nucleoside numbernig) through the introduction of an additional hydroxymethyl group, have been synthesized.Both (R) and (S) enantiomeric series were investigated.The methodologies developed have generality and the presence of the hydroxymethyl group trans to the base may be used to introduce a wide variety of functionalities at this position.