143191-83-7

Upstream product

• 532-20-7 D-xylofuranose 
• 143191-76-8 1,4-anhydro-5-O-benzoyl-3-deoxy-2-O-p-toluenesulfonyl-D-ribitol 
• 55735-86-9 3,5-O-dibenzyloxy-1,2-O-isorpopylidene-α-D-ribofuranose 
• 55775-39-8 1-O-methyl-3,5-di-O-benzyl-D-ribofuranoside 
• 65-71-4 thymin 
• 151825-71-7 Toluene-4-sulfonic acid (3S,4R,5R)-4-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-3-yl ester 
• 138679-69-3 1,4-anhydro-3,5-di-O-benzyl-D-ribitol 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 143191-74-6 methyl 5-O-benzoyl-3-deoxy-D-erythro-pentofuranose 
• 143191-75-7 2(S)-(O-benzoylmethyl)tetrahydrofuran-4(R)-ol 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 4105-29-7 [(3aR,5S,6aR)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzoate 
• 238758-60-6 [(2S,4R)-4-hydroxytetrahydrofuran-2-yl]methyl p-nitrobenzoate 

Relevant academic research and scientific papers

THE SYNTHESIS OF (S) AND (R) ENANTIOMERS OF NOVEL HYDROXYMETHYLATED ISODIDEOXYNUCLEOSIDES

Novel isomeric dideoxynucleosides, with symmetry introduced at the 2'-position (4'-position using normal nucleoside numbernig) through the introduction of an additional hydroxymethyl group, have been synthesized.Both (R) and (S) enantiomeric series were investigated.The methodologies developed have generality and the presence of the hydroxymethyl group trans to the base may be used to introduce a wide variety of functionalities at this position.

2'isodideoxy-β-D-nucleosides as stable antiviral agents

The present invention is concerned wtih new 2'-isomeric 2 2',3'-dideoxy-2'β-D-nucleosides and their derivatives where the base moiety has β-stereochemistry but is transposed from the normal 1'-position to the 2'-position and the carbohydrate moiety has th

Synthesis and anti-HIV activity of isonucleosides

A series of isomeric 2',3'-dideoxynucleosides which contains a modified carbohydrate moiety has been prepared. This class of compounds was designed to mimic the activity of known anti-HIV dideoxynucleosides, while imparting enhanced chemical and enzymatic