143191-78-0

Basic information

• Product Name: Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester
• Synonyms: Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester
• CAS NO: 143191-78-0
• Molecular Weight: 221.256
• Mol File: 143191-78-0.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester(143191-78-0)
• EPA Substance Registry System: Benzoic acid (2S,4S)-4-amino-tetrahydro-furan-2-ylmethyl ester(143191-78-0)

Safety Data

• Hazardous Substances Data: 143191-78-0(Hazardous Substances Data)

Upstream product

• 143191-74-6 methyl 5-O-benzoyl-3-deoxy-D-erythro-pentofuranose 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 160999-15-5 5-O-benzoyl-3-O-(1-imidazolylthiocarbonyl)-1,2-O-isopropylidene-α-D-xylofuranose 
• 98-88-4 benzoyl chloride 
• 143191-75-7 2(S)-(O-benzoylmethyl)tetrahydrofuran-4(R)-ol 
• 4105-29-7 [(3aR,5S,6aR)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzoate 
• 160999-11-1 4(S)-azido-2(S)-(O-benzoylmethyl)tetrahydrofuran 
• 143191-76-8 1,4-anhydro-5-O-benzoyl-3-deoxy-2-O-p-toluenesulfonyl-D-ribitol 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 

Downstream Products

• 160999-14-4 4(S)-<3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl>-2(S)-(p-O-toluenesulfonylmethyl)tetrahydrofuran 
• 160999-12-2 N-<<<(2S,4S)-2-(O-benzoylmethyl)tetrahydrofuranyl>amino>carbonyl>-3-ethoxy-2-propenamide 

Relevant articles and documents

A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity

(E)-5-(2-Bromovinyl)isodideoxyuridine (BVisoDDU), synthesized on the basis of molecular modeling, is selectively active against HSV-1 (three different strains) but inactive against HSV-2. Unlike BVDU, BVisoDDU is completely resistant to cleavage by thymidine phosphorylase. BVisoDDU is also the first nucleoside analogue lacking OH groups at both the 2′- and 3′-position that shows pronounced activity against HSV-1 replication.

Novel isomeric dideoxynucleosides as potential antiviral agents

Novel isomeric dideoxynucleosides with S,S absolute stereochemistry and involving the transposition of the base moiety from the normal 1'- to the 2'-position have been regiospecifically and stereospecifically synthesized. The synthetic approaches involved