14320-58-2

Basic information

• Product Name: 4-methyl-2-phenylpentanoic acid
• CAS NO: 14320-58-2
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.2542
• Mol File: 14320-58-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 298.3°C at 760 mmHg
• Flash Point: 195.4°C
• Density: 1.044g/cm³
• Vapor Pressure: 0.000573mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: 4-methyl-2-phenylpentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-phenylpentanoic acid(14320-58-2)
• EPA Substance Registry System: 4-methyl-2-phenylpentanoic acid(14320-58-2)

Safety Data

• Hazardous Substances Data: 14320-58-2(Hazardous Substances Data)

Usage

General Description

4-methyl-2-phenylpentanoic acid, also known as 4-methyl-2-phenylvaleric acid, is an organic compound with the chemical formula C12H16O2. It is classified as a carboxylic acid and is a white crystalline solid at room temperature. 4-methyl-2-phenylpentanoic acid is commonly used in the production of pharmaceuticals, as well as in the synthesis of various other organic compounds. It is also known for its sweet, floral odor, making it a popular choice as a fragrance ingredient. Additionally, 4-methyl-2-phenylpentanoic acid has been studied for its potential therapeutic applications, including its anti-inflammatory and antioxidant properties.

Upstream product

• 100-42-5 styrene 
• 124-38-9 carbon dioxide 
• 75-26-3 isopropyl bromide 
• 58929-89-8 methyl 4-methyl-2-phenylpentanoate 
• 101-41-7 benzeneacetic acid methyl ester 
• 103-82-2 phenylacetic acid 
• 513-38-2 Isobutyl iodide 
• 140-29-4 phenylacetonitrile 
• 1068-55-9 isopropylmagnesium chloride 
• 78-77-3 Isobutyl bromide 
• 2049-94-7 (3-methylbutyl)benzene 
• 20215-56-9 5,5-dimethyl-3-phenyldihydrofuran-2(3H)-one 
• 5558-31-6 4-methyl-2-phenylpentanenitrile 
• 492-38-6 2-phenylacrylic acid 

Downstream Products

• 605680-32-8 N-methoxy-N-methyl-4-methyl-2-phenylpentanamide 
• 103392-12-7 5-Methyl-3-phenyl-2-hexanone 
• 605680-34-0 2-azido-5-methyl-3-phenylhexane 
• 610791-34-9 2-amino-5-methyl-3-phenylhexane 
• 605680-33-9 5-methyl-3-phenyl-2-hexanol 
• 1392493-50-3 4-methyl-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)pentanamide 
• 145074-64-2 1-diazo-5-methyl-3-phenyl-2-hexanone 
• 407578-54-5 isobutylphenylketene 

Relevant articles and documents

Iron-Catalyzed Asymmetric Decarboxylative Azidation

The first iron-catalyzed asymmetric azidation of benzylic peresters has been reported with trimethylsilyl azide (TMSN3) as the azido source. Hydrocarbon radicals that lack of strong interactions were capable to be enantioselectively azidated. The reaction features good functional group tolerance, high yields, and mild conditions. The chiral benzylic azides can further be used in click reaction, phosphoramidation, and reductive amination, which demonstrate the synthetic values of this reaction.

Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand

A unique example of Pd-catalyzed decarboxylative dehydrogenation of fully substituted N-acyl allyl enol carbonates is enabled by a new electron deficient phosphinooxazoline (PHOX) ligand. The reaction proceeds from the Z-enol carbonate to provide dehydrogenation products exclusively in high E/Z selectivity, while the E-enol carbonate provides the α-allylation product with only minor dehydrogenation. The reaction proceeds with a broad scope of Z-enol carbonates derived from N-acyl indoles to furnish acyclic formal α,β-unsaturated ester equivalents.

Preparation method of carboxylic acid compound

The invention provides a preparation method of a carboxylic acid compound. The preparation method comprises the following step of taking a lactone component to react with hydrogen in the presence of a compound catalyst to obtain the carboxylic acid compound. The compound catalyst comprises a hydrogenation catalyst and Lewis acid. In the presence of the compound catalyst comprising the hydrogenation catalyst and the Lewis acid, the lactone component is subjected to hydrogenation ring-opening reaction to obtain the carboxylic acid compound. The preparation method has the advantages of moderate reaction conditions and high yield; compared with a traditional method, less byproducts are generated, green and chemical requirements are met and the industrial value is better.