1434652-66-0Relevant academic research and scientific papers
ACC inhibitor and application thereof
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, (2021/05/12)
The invention provides a compound suitable for being used as an acetyl CoA carboxylase (ACC) inhibitor, in particular a thienopyridine derivative, and application of the compound in preparation of medicines for treating metabolic diseases, cancers or other proliferative diseases.
SPIRO COMPOUND AND MEDICAL USES THEREOF
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, (2021/11/04)
The present invention relates to a spiro compound and medical uses thereof. Specifically, the present invention relates to a spiro compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the s
NOVEL METHOD FOR PREPARING (2R)-2-(2-METHOXYPHENYL)-2-(OXANE-4-YLOXY)ETHANE-1-OL COMPOUND, AND INTERMEDIATE USED THEREIN
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Paragraph 0102; 0104-0107, (2020/09/22)
A novel method for preparing a compound of Chemical Formula 1 is disclosed. The method includes a step of obtaining a compound of Chemical Formula 1 by performing a reduction reaction on a compound of Chemical Formula 2; and an intermediate used therein. According to the preparation method of the present invention, the compound of Chemical Formula 1, which is useful for the production of an acetyl-CoA carboxylase (ACC) inhibitor, can be mass-produced more simply and efficiently than that of a conventional method:
Preparation method of thienopyrimidinedione compound
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, (2020/02/20)
The invention provides a preparation method of a compound shown as a general formula c, wherein the definition of substituent is as defined in the specification. Please see the specification for the formula.
CYANO SUBSTITUTED HETEROARYLPYRIMIDINONE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
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, (2020/04/24)
The present invention relates to a cyano-substituted heteroarylpyrimidinone derivative represented by formula (I), a preparation method therefor and a use thereof as a therapeutic agent, in particular a use as an acetyl-CoA carboxylase (ACC) inhibitor, an
Preparation method of ACC inhibitor and intermediate thereof
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, (2019/06/12)
The invention relates to the technical field of organic compound synthesis, in particular to a . The preparation method of the intermediate of the ACC inhibitor comprises the following steps: a, performing a halogenation reaction on a compound I to obtain
PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
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, (2018/09/20)
The present disclosure provides solid forms, including a salt or co-crystal, of Compound I which exhibits Acetyl-CoA carboxylase ("ACC") inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps f
ESTER ACC INHIBITORS AND USES THEREOF
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, (2017/07/06)
The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
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, (2017/09/15)
The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
ACC INHIBITORS AND USES THEREOF
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, (2013/05/22)
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
