14351-66-7

Basic information

• Product Name: ABIETIC ACID SODIUM SALT
• Synonyms: sodiumabietate,technical;SODIUM ABIETATE;ABIETIC ACID SODIUM SALT 85+%;1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, sodium salt, (1R,4aR,4bR,10aR)-;(1R)-1,2,3,4,4a,4bα,5,6,10,10aα-Decahydro-7-isopropyl-1,4aβ-dimethyl-1α-phenanthrenecarboxylic acid sodium salt;ABIETIC ACID SODIUM;ABIETIC ACID SODIUM SALT;-7-(1-methylethyl)-,sodiumsalt,[1theta-(1alpha,4abeta,4balpha,10aalpha)
• CAS NO: 14351-66-7
• Molecular Formula: C₂₀H₂₉O₂*Na
• Molecular Weight: 324.43
• EINECS: 238-313-1
• Product Categories: Biochemistry;Terpenes;Terpenes (Others)
• Mol File: 14351-66-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 439.5 °C at 760 mmHg
• Flash Point: 208.1 °C
• Appearance: gray powder complex
• Vapor Pressure: 5.96E-09mmHg at 25°C
• CAS DataBase Reference: ABIETIC ACID SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: ABIETIC ACID SODIUM SALT(14351-66-7)
• EPA Substance Registry System: ABIETIC ACID SODIUM SALT(14351-66-7)

Safety Data

• Hazardous Substances Data: 14351-66-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder. Soluble in water. Com- bustible.

Uses

Soap making, paper coating.

InChI:InChI=1/C20H30O2.Na/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22;/h7,12-13,16-17H,5-6,8-11H2,1-4H3,(H,21,22);/q;+1/p-1/t16-,17+,19+,20+;/m0./s1

Synthetic route

acetyl chloride (75-36-5) + abietic acid sodium salt (14351-66-7) → 7,13-Abietadien-18-oic acid anhydride (19897-44-0) + acetic (1R,4aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydropbenanthrene-1-carboxylic anhydride

Conditions	Yield
In diethyl ether at 20℃; for 3h; Condensation;	A n/a B 41%

benzoyl chloride (98-88-4) + abietic acid sodium salt (14351-66-7) → 7,13-Abietadien-18-oic acid anhydride (19897-44-0) + Abietic benzoic anhydride

Conditions	Yield
In diethyl ether at 25℃; for 11h; Acylation;	A n/a B 34%

abietic acid sodium salt (14351-66-7) + Stearoyl chloride (112-76-5) → Abietic stearic anhydride

Conditions	Yield
In diethyl ether at 35℃; for 11h; Acylation;	21%

abietic acid sodium salt (14351-66-7) → (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-isopropenyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid + 2α-hydroxyabietic acid (82540-29-2) + (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-(1-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid (82540-35-0) + (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-(2-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

Conditions	Yield
at 35℃; for 23h; aerob fermentation by Mortierella isabellina;
at 35℃; for 14h; aerob fermentation by Mortierella isabellina;

abietic acid sodium salt (14351-66-7) → (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-(1-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid (82540-35-0) + (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-(2-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

Conditions	Yield
at 35℃; for 27h; aerob fermentation by Mortierella isabellina;

methanesulfonyl chloride (124-63-0) + abietic acid sodium salt (14351-66-7) → Abietic methanesulfonic anhydride

Conditions	Yield
In diethyl ether Condensation; Heating;

p-toluenesulfonyl chloride (98-59-9) + abietic acid sodium salt (14351-66-7) → Abietic p-toluenesulfonic anhydride

Conditions	Yield
In diethyl ether Condensation; Heating;

abietic acid sodium salt (14351-66-7) → methyl abietate (127-25-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 49 percent / H2SO4 / benzene / 30 h / 65 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 49 percent / H2SO4 / benzene / 30 h / 65 °C View Scheme

abietic acid sodium salt (14351-66-7) → 2-Diethylaminoethyl abietate (105498-97-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: H2SO4 / 2 h / 160 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: H2SO4 / 2 h / 160 °C View Scheme

abietic acid sodium salt (14351-66-7) → ethyl abietate (631-71-0)

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 72 percent / H2SO4 / benzene / 20 h / 78 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 72 percent / H2SO4 / benzene / 20 h / 78 °C View Scheme

abietic acid sodium salt (14351-66-7) → (1R,4aR)-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carboxamide

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 26 percent / NH3 / benzene / 70 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 26 percent / NH3 / benzene / 70 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietohydroxamic acid

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 14 percent / hydroxylamine; NaOH / 32 h / 60 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 14 percent / hydroxylamine; NaOH / 32 h / 60 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietohydrazide

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 33 percent / hydrazine hydrate / 7 h / 120 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 33 percent / hydrazine hydrate / 7 h / 120 °C View Scheme

abietic acid sodium salt (14351-66-7) → (1R,4aR)-N,N-diethyl-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carboxamide

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 68 percent / benzene / Heating View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 68 percent / benzene / Heating View Scheme

abietic acid sodium salt (14351-66-7) → Phenyl abietate

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 61 percent / hydroquinone / 3 h / 160 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 61 percent / hydroquinone / 3 h / 160 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietyl phenyl ketone

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 12 g / AlCl3 / 0.5 h / 80 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 12 g / AlCl3 / 0.5 h / 80 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietoylurea

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 20 percent / pyridine / 6 h / 125 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 20 percent / pyridine / 6 h / 125 °C View Scheme

abietic acid sodium salt (14351-66-7) → (1R,4aR,4bR,10aR)-7-isopropyl-1,4a-dimethyl-N-phenyl-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carboxamide

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 52 percent / 1,2-dihydroxybenzene / 2 h / Heating View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 52 percent / 1,2-dihydroxybenzene / 2 h / Heating View Scheme

abietic acid sodium salt (14351-66-7) → Abietyl p-methoxyphenyl ketone

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: AlCl3 / 80 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: AlCl3 / 80 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietyl p-methoxyphenyl ketone

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: AlCl3 / 80 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: AlCl3 / 80 °C View Scheme

abietic acid sodium salt (14351-66-7) → N-Abietoylglycine

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 17 percent / pyridine; hydroquinone / H2O / 9 h / 80 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 17 percent / pyridine; hydroquinone / H2O / 9 h / 80 °C View Scheme

abietic acid sodium salt (14351-66-7) → Abietyl abietoylaminomethyl ketone

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 11 h / 25 °C 2: 12 percent / pyridine; hydroquinone / H2O / 16 h / 80 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 3 h / 20 °C 2: 12 percent / pyridine; hydroquinone / H2O / 16 h / 80 °C View Scheme

abietic acid sodium salt (14351-66-7) → (1R,3R,4aR,4bR,10aR)-3-Hydroxy-7-(2-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid methyl ester

Conditions	Yield
Multi-step reaction with 3 steps 1: 27 h / 35 °C / aerob fermentation by Mortierella isabellina 2: 2.) pyridine 3: H2O/KOH / methanol / 5 h View Scheme

abietic acid sodium salt (14351-66-7) → methyl 2α-acetoxy-15-hydroxyabietate

Conditions	Yield
Multi-step reaction with 2 steps 1: 27 h / 35 °C / aerob fermentation by Mortierella isabellina 2: 2.) pyridine View Scheme

abietic acid sodium salt (14351-66-7) → methyl 2α,16-diacetoxyabietate

Conditions	Yield
Multi-step reaction with 2 steps 1: 27 h / 35 °C / aerob fermentation by Mortierella isabellina 2: 2.) pyridine View Scheme

Downstream Products

• 631-71-0 ethyl abietate 
• 127-25-3 methyl abietate 
• 19897-44-0 7,13-Abietadien-18-oic acid anhydride