143699-05-2

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazol-5-ol, 4,4'-[(4-methylphenyl)methylene]bis[3-methyl-1-phenylis used as a potential pharmaceutical compound for its unique chemical structure and properties. The pyrazole and phenol groups can be utilized for the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, 1H-Pyrazol-5-ol, 4,4'-[(4-methylphenyl)methylene]bis[3-methyl-1-phenylcan be used as a precursor or intermediate in the synthesis of agrochemicals, such as pesticides and herbicides, due to its reactive functional groups.
Used in Materials Science:
1H-Pyrazol-5-ol, 4,4'-[(4-methylphenyl)methylene]bis[3-methyl-1-phenylcan be employed in materials science for the development of new materials with specific properties, such as high thermal stability, chemical resistance, or unique optical characteristics, by leveraging the properties of the pyrazole and phenol groups.
Further research and exploration of the properties and potential uses of 1H-Pyrazol-5-ol, 4,4'-[(4-methylphenyl)methylene]bis[3-methyl-1-phenylare necessary to fully understand its capabilities and applications across different industries.

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 89-25-8 edaravone 
• 53316-56-6 4-(4-methylbenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 100-63-0 phenylhydrazine 
• 141-97-9 ethyl acetoacetate 
• 19865-55-5 N-(4-methylbenzylidene)aniline oxide 

Relevant academic research and scientific papers

SbCl5/SiO2nanoparticles: An efficient and reusable reagent for the synthesis of 4,4′-(arylmethylene)bis(1 h -pyrazol-5-ol) derivatives in water

An efficient and eco-friendly method for the synthesis of 4,4-(arylmethylene)bis(1H-pyrazol-5-ol) derivatives is described by tandem Knoevenagel-Michael reaction between aromatic aldehydes and 3-methyl-1-phenyl-2-pyrazoline-5-one in the presence of nanosi

Catalyst-free tandem Knoevenagel-Michael reaction of aldehydes and pyrazolin-5-one: Fast and convenient approach to medicinally relevant 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol)s

Catalyst-free tandem Knoevenagel-Michael reaction of aryl aldehydes and two equivalents of 3-methyl-1-phenyl-2-pyrazolin-5-one results in fast (5 min) formation of medicinally relevant 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol)s in excellent 93%-99% yield.

In situ decorated Mn–lysine complex on magnetic nanoparticles as a novel and reusable nanocatalyst in the synthesis of 4,4′-(arylmethylene)-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ols) derivatives

In this work, we report a new and recoverable catalyst by anchoring the Mn–Lysine complex on the surface of CoFe2O4 magnetic nanoparticles through a simple, rapid and eco-friendly procedure. The successful synthesis of this nanostruc

Synthesis of sulfonated melamine-functionalized Fe3O4@SiO2@Si–(CH2)3@melamine nanoparticles and its application in the synthesis of 4,4’-(aryl methylene)bis(3-methyl-1H-pyrazol-5-ol)s and hexahydroqui

In this work, sulfonated melamine-functionalized Fe3O4@SiO2@Si-(CH2)3@melamine nanoparticles were prepared through a simple approach and characterized by energy dispersive X-ray analysis (EDX), field

Zirconium@guanine@MCM-41 nanoparticles: An efficient heterogeneous mesoporous nanocatalyst for one-pot, multi-component tandem Knoevenagel condensation–Michael addition–cyclization Reactions

MCM-41-supported nanoscale guanine bonded with Zr (IV) was prepared using sol–gel method and characterized by FT-IR, Raman, XRD, BET, TGA, EDX, ICP, AAS, X-Ray mapping, SEM and TEM techniques. This compound was employed as an efficient, chemoselectivity a

Guanine-La complex supported onto SBA-15: A novel efficient heterogeneous mesoporous nanocatalyst for one-pot, multi-component Tandem Knoevenagel condensation–Michael addition–cyclization Reactions

In this work, we present a simple, environmentally-friendly and economical route for the preparation of a novel lanthanum (III) organometallic complex immobilized onto a highly stable mesoporous silica SBA-15 (La-guanine@SBA-15) using an inexpensive and s

Pd(0)-guanidine?MCM-41: a very effective catalyst for rapid production of bis (pyrazolyl)methanes

In this research, a rapid, green and efficient protocol for synthesis of bis (pyrazolyl)methane derivatives in the presence of Pd(0)-guanidine?MCM-41 catalysts under solvent-free conditions by the following two methods has been reported: (i) via the one-p

Chitosan-SO3H (CTSA) an efficient and biodegradable polymeric catalyst for the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol) and α-amidoalkyl-β-naphthol’s

An efficient, green procedure for the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol) and α-amidoalkyl-β-naphthol’s using biodegradable polymeric catalyst chitosan-SO3H (CTSA), is operationally easy to prepare by mixing chitosan and chlor

Synthesis of a new Ni complex supported on CoFe2O4 and its application as an efficient and green catalyst for the synthesis of bis(pyrazolyl)methane and polyhydroquinoline derivatives

Effective research in green chemistry requires new and applicable synthetic techniques. In this regard, for the first time, a green method is reported for the immobilization of iminodiacetic acid-Ni complex on the surface of CoFe2O4

A simple, rapid and effective protocol for synthesis of bis(pyrazolyl)methanes using nickel–guanidine complex immobilized on MCM-41

Abstract: In this paper, a rapid, easy and very efficient method for the synthesis of bis(pyrazolyl)methanes has been reported in the presence of nickel–guanidine complex immobilized on MCM-41 (MCM-41@Gu@Ni) as a recyclable nanocatalyst. This mesoporous s