14377-33-4Relevant articles and documents
Dynamic covalent approach to [2]- and [3]rotaxanes by utilizing a reversible thiol-disulfide interchange reaction
Furusho, Yoshio,Oku, Tomoya,Hasegawa, Toshihide,Tsuboi, Akiyoshi,Kihara, Nobuhiro,Takata, Toshikazu
, p. 2895 - 2903 (2003)
A dynamic covalent approach to disulfide-containing [2]- and [3]rotaxanes is described. Symmetrical dumbbell-shaped compounds with two secondary ammonium centers and a central located disulfide bond were synthesized as components of rotaxanes. The rotaxan
Synthesis and Band Gap Analysis of Designed Porphyrin Derivatives Containing Electron Donating and Accepting Group
Chang, In-Jung,Jeon, Yea-Sel,Hwang, Kwang-Jin
, p. 173 - 179 (2019/02/14)
Symmetric (DD, AA1–AA5) and non-symmetric (DA1) porphyrin derivatives were synthesized through McDonald coupling of bispyrrole 2D, 2A1–2A5 with the corresponding aldehyde 3 or diol 6 as a key step. The UV–Vis spectrum and CV of those porphyrins were measu
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
Igumnova, Elizaveta M.,Mishchenko, Ekaterina,Haug, Tor,Blencke, Hans-Matti,Sollid, Johanna U. Ericson,Fredheim, Elizabeth G. Aarag,Lauksund, Silje,Stensv?g, Klara,Str?m, Morten B.
, p. 5884 - 5894 (2016/11/09)
A library of small aminobenzamide derivatives was synthesised to explore a cationic amphipathic motif found in marine natural antimicrobials. The most potent compound E23 displayed minimal inhibitory concentrations (MICs) of 0.5–2 μg/ml against several Gr
Catalytic ship-in-a-bottle assembly within hollow porous nanocapusles
Ehterami, Nasim,Dergunov, Sergey A.,Ussipbekova, Yenlik,Birman, Vladimir B.,Pinkhassik, Eugene
supporting information, p. 481 - 485 (2014/02/14)
Large molecules can be assembled from small components exclusively inside hollow nanocapsules with the help of entrapped catalysts. Phenyl isocyanates enter the capsules through nanopores in the capsule shells and form cyclic trimers that remain entrapped
Facile route to an all-organic, triply threaded, interlocked structure by templated dynamic clipping
Pun, Andrew,Hanifi, David A.,Kiel, Gavin,O'Brien, Evan,Liu, Yi
supporting information, p. 13119 - 13122 (2013/03/13)
[2]Rotaxanes are a class of mechanically interlocked molecules which are generally depicted by an "axle-in-wheel" model, in which a dumbbell-shaped linear component is threaded through a macrocyclic component (Scheme 1 a). Functionalization of the rotaxan
Identification of a foldaxane kinetic byproduct during guest-induced single to double helix conversion
Gan, Quan,Ferrand, Yann,Chandramouli, Nagula,Huc, Ivan,Kauffmann, Brice,Aube, Christophe,Dubreuil, Didier
supporting information, p. 15656 - 15659,4 (2020/08/24)
An aromatic oligoamide sequence was designed and synthesized to fold in a single helix having a large cavity and to behave as a host for a dumbbell-shaped guest derived from tartaric acid. NMR, molecular modeling, and circular dichroism (CD) evidence demo
2-ARYLTHIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS
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Page/Page column 64, (2010/11/28)
The invention encompasses compounds of Formula I or pharmaceutically acceptable salts thereof, which are modulators of the CXCR3 chemokine receptor function useful for the treatment or prevention of pathogenic inflammatory processes, autoimmune diseases or graft rejection processes. Methods of use and pharmaceutical compositions are also encompassed.
Structural Studies on Hydrogen-Bonding Receptors for Barbiturate Guests that Use Metal Ions as Allosteric Inhibitors
Al-Sayah, Mohammed H.,McDonald, Robert,Brand, Neil R.
, p. 173 - 182 (2007/10/03)
Receptor 1 was designed to bind barbiturate substrates through a six-point hydrogen-bonding motif only in the absence of metal allosteric cofactors. It was predicted that the binding of metal ions by bipyridine ligands in 1 would result in a geometric change in the receptor to inhibit substrate recognition. However, receptor 1 showed minimal affinity for the barbiturate quests even in the absence of the metal. Binding studies on model compounds 2, 3, 5, and 6 revealed that the inactivity of 1 is due to an intramolecular hydrogen bond between the N-H donor groups and the nitrogen atoms on the first heterocycle of the bipyridine ligands. This intramolecular hydrogen-bonding was eliminated by altering the position of the tether between the bipyridine ligands and the active site to produce receptor 7. Consequently, the high affinity exhibited by 7 for the barbiturate substrate (Ka = 2.8 +/- 0.7*103 M-1 in 9 : 1 CD2Cl2/CD3CN) was significantly reduced by the addition of ZnII ions as a negative allosteric co-factor.
LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS
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, (2008/06/13)
A ligand useful to form a metallocene olefin polymerization catalyst comprises:wherein at least R3 and R4 are substituents having at least a bulk of a t-butyl group and, optionally, wherein R1 or R2 may be a bulky substituent group.