1437778-75-0

Upstream product

• 1192063-72-1 racemic tert-butyl 4-[(1Z)-4-(benzyloxy)but-1-en-1-yl]piperidine-1-carboxylate 
• 1437778-81-8 2-[(1S,2R)-2-{1-[5-(methoxymethyl)pyrimidin-2-yl]piperidin-4-yl}cyclopropyl]ethanol 
• 1416366-34-1 2-chloro-5-(methoxymethyl)pyrimidine 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 1046816-75-4 2-chloro-5-hydroxymethyl-pyrimidine 
• 64-18-6 formic acid 
• 1437779-20-8 2-[2-fluoro-4-(2-{(1S,2R)-2-[1-[5-(methoxymethyl)pyrimidine-2-yl]piperidin-4-yl]cyclopropyl}ethoxy)phenyl]acetohydrazide 
• 1402554-67-9 benzyl 4-[(1R,2S)-2-(2-hydroxyethyl)cyclopropyl]piperidine-1-carboxylate 
• 1192063-81-2 tert-butyl 4-[(1Z,4R)-5-(benzyloxy)-4-hydroxypent-1-en-1-yl]piperidine-1-carboxylate 
• 1192063-78-7 tert-butyl 4-[(4R)-5-(benzyloxy)-4-hydroxypent-1-yn-1-yl]piperidine-1-carboxylate 
• 1437778-94-3 {2-fluoro-4-[2-((1S,2R)-2-{1-[5-(methoxymethyl)pyrimidin-2-yl]piperidin-4-yl}cyclopropyl)ethoxy]phenyl}acetic acid 
• 287192-97-6 4-ethynyl-piperidine-1-carboxylic acid tert-butyl ester 
• 1437778-93-2 methyl {2-fluoro-4-[2-((1S,2R)-2-{1-[5-(methoxymethyl)pyrimidin-2-yl]piperidin-4-yl}cyclopropyl)ethoxy]phenyl}acetate 
• 91361-59-0 methyl 2-(2-fluoro-4-hydroxyphenyl)acetate 

Relevant academic research and scientific papers

SUBSTITUTED CYCLOPROPYL COMPOUNDS USEFUL AS GPR119 AGONISTS

Substituted cyclopropyl compounds of the formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included