14383-62-1

Usage

Uses

Used in Pharmaceutical Industry:
Benzenemethanol, a-[(1S)-1-(methylamino)ethyl]-,acetate (ester), hydrochloride, (aR)(9CI) is used as a medication or drug for its potential therapeutic effects in treating various medical conditions. Its specific application in the pharmaceutical industry is due to its chemical structure and properties that may contribute to its efficacy in addressing certain health issues.
Note: Since the provided materials do not specify the exact medical conditions or the exact reasons for its use, the above usage is a general statement based on the information given. Further details on its specific applications would require additional information or research.

Synthetic route

ephedrine hydrochloride (50-98-6) + acetyl chloride (75-36-5) → acetic acid-((1R,2S)-2-methylamino-1-phenyl-propylester); hydrochloride (14383-62-1)

Conditions	Yield
With sulfur dioxide

methanol (67-56-1) + diisobutylamine (110-96-3) + acetic acid-((1R,2S)-2-methylamino-1-phenyl-propylester); hydrochloride (14383-62-1) → (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid (2272-83-5)

Conditions	Yield
Zeitlicher Verlauf der Isomerisierung;

diisobutylamine (110-96-3) + chloroform (67-66-3) + acetic acid-((1R,2S)-2-methylamino-1-phenyl-propylester); hydrochloride (14383-62-1) → (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid (2272-83-5)

Conditions	Yield
Zeitlicher Verlauf der Isomerisierung;

acetic acid-((1R,2S)-2-methylamino-1-phenyl-propylester); hydrochloride (14383-62-1) + aqueous potassium carbonate → (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid (2272-83-5)

Upstream product

• 50-98-6 ephedrine hydrochloride 
• 75-36-5 acetyl chloride 
• 50-98-6 (±)-pseudoephedrine hydrochloride 
• 108-24-7 acetic anhydride 
• 134-71-4 rac-ephedrine hydrochloride 

Downstream Products

• 2272-83-5 (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid 
• 2272-83-5 N-((1RS,2SR)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-acetamide