143919-34-0

Basic information

• Product Name: Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3R,4R)-
• Synonyms: Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3R,4R)-
• CAS NO: 143919-34-0
• Molecular Formula: C₁₇H₂₇NO
• Molecular Weight: 261.40238
• Mol File: 143919-34-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3R,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3R,4R)-(143919-34-0)
• EPA Substance Registry System: Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3R,4R)-(143919-34-0)

Safety Data

• Hazardous Substances Data: 143919-34-0(Hazardous Substances Data)

Upstream product

• 149541-62-8 C₁₉H₂₉NO₄ 
• 149541-62-8 cis-(-)-carbonic acid ethyl 1,3-dimethyl-4-[3-(l-methylethoxy)phenyl]-4-piperidinyl ester 
• 145340-44-9 1,3-dimethyl-4-[3-(propan-2-yloxy)phenyl]-4-piperidinol 
• 4629-80-5 1,3-dimethyl-4-piperidinone 
• 131738-73-3 3-(isopropyloxy)phenylbromide 
• 143919-32-8 (R)-1,2,3,4-tetrahydro-1,3-dimethyl-4-<3-(1-methylethoxy)phenyl>pyridine 

Downstream Products

• 145678-86-0 (3R,4R)-3,4-dimethyl-4-<3-(1-methylethoxy)phenyl>piperidinecarboxylic acid phenyl ester 
• 156130-41-5 ADL 08-0011 
• 145603-86-7 (+)-<<2'(S)-<<4(R)-3-(hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl>methyl>-1-oxo-3-phenylpropyl>amino>acetic acid 2-methylpropyl ester 
• 156053-89-3 Entereg 
• 156130-44-8 2‐((R)‐2‐benzyl‐3‐((3R,4R)‐4‐(3‐hydroxyphenyl)‐3,4‐dimethylpiperidin‐1‐yl)propanamido)acetic acid 
• 1184775-81-2 C₁₇H₂₇NO*C₂₀H₁₈O₈ 
• 170098-29-0 methyl (αS,3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-α-(phenylmethyl)-1-piperidinepropanoate 
• 170098-39-2 methyl (3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinepropanoate 
• 119193-09-8 (+)-1-(3(S)-3-hydroxy-3-cyclohexylpropyl)-3(R),4(R)-dimethyl-4-(3-hydroxyphenyl)piperidine 
• 119193-19-0 3-[(3R,4R)-3,4-dimethylpiperidin-4-yl]phenol 

Relevant articles and documents

Synthesis and characterization of all possible diastereoisomers of alvimopan

Isolation of all possible diastereomers of alvimopan 1 was found to be challenging. In order to perform cut off studies during analytical method development, it was mandatory to synthesize and characterize all the diastereomeric impurities. Here in, our efforts toward the synthesis and isolation of alvimopan (1) diastereomers are discussed.

Preparation of substituted tetrahydropyridines

A process for preparing certain 1,3,4,4-tetrasubstituted-1,2,3,4-tetrahydropyridines is provided as well as certain 4-carbonate-1,3,4-trisubstituted-piperidines.